Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | chpSB/PRK09812-ChpS |
Location | 3776449..3777044 | Replicon | chromosome |
Accession | NZ_CP076838 | ||
Organism | Leclercia pneumoniae strain 49125 |
Toxin (Protein)
Gene name | chpB | Uniprot ID | - |
Locus tag | KQ929_RS18445 | Protein ID | WP_207292876.1 |
Coordinates | 3776449..3776799 (-) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | chpS | Uniprot ID | - |
Locus tag | KQ929_RS18450 | Protein ID | WP_040077462.1 |
Coordinates | 3776793..3777044 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KQ929_RS18430 (KQ929_18430) | 3772778..3773734 | - | 957 | WP_046886414.1 | galactofuranose ABC transporter substrate-binding protein YtfQ | - |
KQ929_RS18435 (KQ929_18435) | 3774044..3774574 | + | 531 | WP_040077459.1 | inorganic diphosphatase | - |
KQ929_RS18440 (KQ929_18440) | 3774829..3776412 | + | 1584 | WP_207292877.1 | methyl-accepting chemotaxis protein | - |
KQ929_RS18445 (KQ929_18445) | 3776449..3776799 | - | 351 | WP_207292876.1 | type II toxin-antitoxin system ChpB family toxin | Toxin |
KQ929_RS18450 (KQ929_18450) | 3776793..3777044 | - | 252 | WP_040077462.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
KQ929_RS18455 (KQ929_18455) | 3777268..3777612 | - | 345 | WP_040077463.1 | gamma-glutamylcyclotransferase | - |
KQ929_RS18460 (KQ929_18460) | 3777615..3781391 | - | 3777 | WP_207292875.1 | translocation/assembly module TamB domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12425.26 Da Isoelectric Point: 5.0196
>T206529 WP_207292876.1 NZ_CP076838:c3776799-3776449 [Leclercia pneumoniae]
MVRALTYDRGDIVLVNFSPANGHEQQGAGRPALVLSLSTFNQTGMVLVAPITQGGSYARYAGFAVPVSCEEGDVQGAVLV
NQLRMMDLHARQAKKIAIATDEVVEDALLRLQAIID
MVRALTYDRGDIVLVNFSPANGHEQQGAGRPALVLSLSTFNQTGMVLVAPITQGGSYARYAGFAVPVSCEEGDVQGAVLV
NQLRMMDLHARQAKKIAIATDEVVEDALLRLQAIID
Download Length: 351 bp
>T206529 NZ_CP102478:c6801-6391 [Burkholderia cenocepacia]
ATGACGCTGTACCTGCTCGATACCAACATTTTGTCGAACGTGATCCGCGACCCGCGCGGCGCATGCGCCACCCGGATCGG
AGAAACCCCGCCGGAGCAAGTGTGCACCTCGATCGTCGTCGCGGCGGAACTGCGGTTCGGCGTCTGGAAGCGTGGCTCTT
CGACGCTCGCGCAGCGCGTCGAGCAGCTGCTCGCAAGCCTGACCGTGTTGCCGCTGCAGCCCGACGCGGACCGCTGCTAC
GGGCGATTGCGGGCCGAGCTCGAGAAGCAAGGCCAGTTGATCGGCGCCAACGACATGCTGATCGCCGCGCATGCGTTGGC
CGTCGACGCGGTCCTGGTCACGGACAATACGGCTGAGTTCACCCGCGTTGCCGGGCTGCCGGTCGAAAACTGGCTGCGGC
CAGCGACGTAA
ATGACGCTGTACCTGCTCGATACCAACATTTTGTCGAACGTGATCCGCGACCCGCGCGGCGCATGCGCCACCCGGATCGG
AGAAACCCCGCCGGAGCAAGTGTGCACCTCGATCGTCGTCGCGGCGGAACTGCGGTTCGGCGTCTGGAAGCGTGGCTCTT
CGACGCTCGCGCAGCGCGTCGAGCAGCTGCTCGCAAGCCTGACCGTGTTGCCGCTGCAGCCCGACGCGGACCGCTGCTAC
GGGCGATTGCGGGCCGAGCTCGAGAAGCAAGGCCAGTTGATCGGCGCCAACGACATGCTGATCGCCGCGCATGCGTTGGC
CGTCGACGCGGTCCTGGTCACGGACAATACGGCTGAGTTCACCCGCGTTGCCGGGCTGCCGGTCGAAAACTGGCTGCGGC
CAGCGACGTAA
Antitoxin
Download Length: 84 a.a. Molecular weight: 9096.50 Da Isoelectric Point: 4.4384
>AT206529 WP_040077462.1 NZ_CP076838:c3777044-3776793 [Leclercia pneumoniae]
MRITIKKWGNSAGVIIPGAIMKELNMQVGQSMEAQVVDNQVVLKPLSKRYTLEELLAQCDPNAAPATEDELWGNAGPMGN
EVW
MRITIKKWGNSAGVIIPGAIMKELNMQVGQSMEAQVVDNQVVLKPLSKRYTLEELLAQCDPNAAPATEDELWGNAGPMGN
EVW
Download Length: 252 bp
>AT206529 NZ_CP102478:c7040-6798 [Burkholderia cenocepacia]
ATGCCAACCCATGACACCCGCCACGCGCGCCTGTTTCGCAACGGGCGAAGCCAGGCCGTGCGGATCCCGCGCGAATTCGA
ATTGCCGGTCTCGGAGGTCACCATCCAGCGGGAAGGCCGCCGCTTGATCATTGAGCCCGTGGAGGCCGCGCCCTTGCGTG
AGCTGTTCGCCCAATGGGCCCCGCTGGACGAGACCTTTCCGGACATCGAGGACCTTCCCGCTGAACCGGTCGACATCGAA
TGA
ATGCCAACCCATGACACCCGCCACGCGCGCCTGTTTCGCAACGGGCGAAGCCAGGCCGTGCGGATCCCGCGCGAATTCGA
ATTGCCGGTCTCGGAGGTCACCATCCAGCGGGAAGGCCGCCGCTTGATCATTGAGCCCGTGGAGGCCGCGCCCTTGCGTG
AGCTGTTCGCCCAATGGGCCCCGCTGGACGAGACCTTTCCGGACATCGAGGACCTTCCCGCTGAACCGGTCGACATCGAA
TGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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