Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 3776449..3777044 Replicon chromosome
Accession NZ_CP076838
Organism Leclercia pneumoniae strain 49125

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag KQ929_RS18445 Protein ID WP_207292876.1
Coordinates 3776449..3776799 (-) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag KQ929_RS18450 Protein ID WP_040077462.1
Coordinates 3776793..3777044 (-) Length 84 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQ929_RS18430 (KQ929_18430) 3772778..3773734 - 957 WP_046886414.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
KQ929_RS18435 (KQ929_18435) 3774044..3774574 + 531 WP_040077459.1 inorganic diphosphatase -
KQ929_RS18440 (KQ929_18440) 3774829..3776412 + 1584 WP_207292877.1 methyl-accepting chemotaxis protein -
KQ929_RS18445 (KQ929_18445) 3776449..3776799 - 351 WP_207292876.1 type II toxin-antitoxin system ChpB family toxin Toxin
KQ929_RS18450 (KQ929_18450) 3776793..3777044 - 252 WP_040077462.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
KQ929_RS18455 (KQ929_18455) 3777268..3777612 - 345 WP_040077463.1 gamma-glutamylcyclotransferase -
KQ929_RS18460 (KQ929_18460) 3777615..3781391 - 3777 WP_207292875.1 translocation/assembly module TamB domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(9-114)

Antitoxin

(6-49)


Sequences


Toxin        


Download         Length: 117 a.a.        Molecular weight: 12425.26 Da        Isoelectric Point: 5.0196

>T206529 WP_207292876.1 NZ_CP076838:c3776799-3776449 [Leclercia pneumoniae]
MVRALTYDRGDIVLVNFSPANGHEQQGAGRPALVLSLSTFNQTGMVLVAPITQGGSYARYAGFAVPVSCEEGDVQGAVLV
NQLRMMDLHARQAKKIAIATDEVVEDALLRLQAIID

Download         Length: 351 bp

>T206529 NZ_CP102478:c6801-6391 [Burkholderia cenocepacia]
ATGACGCTGTACCTGCTCGATACCAACATTTTGTCGAACGTGATCCGCGACCCGCGCGGCGCATGCGCCACCCGGATCGG
AGAAACCCCGCCGGAGCAAGTGTGCACCTCGATCGTCGTCGCGGCGGAACTGCGGTTCGGCGTCTGGAAGCGTGGCTCTT
CGACGCTCGCGCAGCGCGTCGAGCAGCTGCTCGCAAGCCTGACCGTGTTGCCGCTGCAGCCCGACGCGGACCGCTGCTAC
GGGCGATTGCGGGCCGAGCTCGAGAAGCAAGGCCAGTTGATCGGCGCCAACGACATGCTGATCGCCGCGCATGCGTTGGC
CGTCGACGCGGTCCTGGTCACGGACAATACGGCTGAGTTCACCCGCGTTGCCGGGCTGCCGGTCGAAAACTGGCTGCGGC
CAGCGACGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9096.50 Da        Isoelectric Point: 4.4384

>AT206529 WP_040077462.1 NZ_CP076838:c3777044-3776793 [Leclercia pneumoniae]
MRITIKKWGNSAGVIIPGAIMKELNMQVGQSMEAQVVDNQVVLKPLSKRYTLEELLAQCDPNAAPATEDELWGNAGPMGN
EVW

Download         Length: 252 bp

>AT206529 NZ_CP102478:c7040-6798 [Burkholderia cenocepacia]
ATGCCAACCCATGACACCCGCCACGCGCGCCTGTTTCGCAACGGGCGAAGCCAGGCCGTGCGGATCCCGCGCGAATTCGA
ATTGCCGGTCTCGGAGGTCACCATCCAGCGGGAAGGCCGCCGCTTGATCATTGAGCCCGTGGAGGCCGCGCCCTTGCGTG
AGCTGTTCGCCCAATGGGCCCCGCTGGACGAGACCTTTCCGGACATCGAGGACCTTCCCGCTGAACCGGTCGACATCGAA
TGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References