Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) virAT/YafQ(toxin)
Location 30271..30814 Replicon plasmid pVir
Accession NZ_CP076837
Organism Campylobacter jejuni X voucher NCTC 13357

Toxin (Protein)


Gene name virT Uniprot ID -
Locus tag N578_RS09455 Protein ID WP_053868684.1
Coordinates 30545..30814 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name virA Uniprot ID A0A5T1CFM5
Locus tag N578_RS09450 Protein ID WP_053868685.1
Coordinates 30271..30555 (+) Length 95 a.a.

Genomic Context

N578_RS09405N578_RS09410N578_RS09415N578_RS09420N578_RS09425N578_RS09430N578_RS09435N578_RS09440N578_RS09445N578_RS09450N578_RS09455N578_RS09460N578_RS09470N578_RS09475N578_RS09465
Location: 25883..26227 (345 bp)
Type: Others
Protein ID: WP_024266121.1
Location: 26241..26549 (309 bp)
Type: Others
Protein ID: WP_011117580.1
Location: 26559..26780 (222 bp)
Type: Others
Protein ID: WP_011799395.1
Location: 27258..27755 (498 bp)
Type: Others
Protein ID: WP_024266124.1
Location: 27850..28284 (435 bp)
Type: Others
Protein ID: WP_115614173.1
Location: 28271..28702 (432 bp)
Type: Others
Protein ID: WP_021357906.1
Location: 28702..29004 (303 bp)
Type: Others
Protein ID: WP_024266116.1
Location: 29193..29561 (369 bp)
Type: Others
Protein ID: WP_115614174.1
Location: 29676..30047 (372 bp)
Type: Others
Protein ID: WP_052835040.1
Location: 30271..30555 (285 bp)
Type: Antitoxin
Protein ID: WP_053868685.1
Location: 30545..30814 (270 bp)
Type: Toxin
Protein ID: WP_053868684.1
Location: 30928..31239 (312 bp)
Type: Others
Protein ID: Protein_42
Location: 33991..34296 (306 bp)
Type: Others
Protein ID: WP_011799398.1
Location: 34296..34538 (243 bp)
Type: Others
Protein ID: WP_052835045.1
Location: 31547..33118 (1572 bp)
Type: Others
Protein ID: WP_115614176.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
N578_RS09405 (N578_09405)25883..26227+345WP_024266121.1hypothetical protein-
N578_RS09410 (N578_09410)26241..26549+309WP_011117580.1hypothetical protein-
N578_RS09415 (N578_09415)26559..26780+222WP_011799395.1hypothetical protein-
N578_RS09420 (N578_09420)27258..27755+498WP_024266124.1hypothetical protein-
N578_RS09425 (N578_09425)27850..28284+435WP_115614173.1hypothetical protein-
N578_RS09430 (N578_09430)28271..28702+432WP_021357906.1hypothetical protein-
N578_RS09435 (N578_09435)28702..29004+303WP_024266116.1hypothetical protein-
N578_RS09440 (N578_09440)29193..29561+369WP_115614174.1hypothetical protein-
N578_RS09445 (N578_09445)29676..30047+372WP_052835040.1hypothetical protein-
N578_RS09450 (N578_09450)30271..30555+285WP_053868685.1hypothetical proteinAntitoxin
N578_RS09455 (N578_09455)30545..30814+270WP_053868684.1type II toxin-antitoxin system YafQ family toxinToxin
N578_RS09460 (N578_09460)30928..31239+312Protein_42hypothetical protein-
N578_RS09465 (N578_09465)31547..33118-1572WP_115614176.1relaxase/mobilization nuclease domain-containing protein-
N578_RS09470 (N578_09470)33991..34296+306WP_011799398.1hypothetical protein-
N578_RS09475 (N578_09475)34296..34538+243WP_052835045.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid-virB4 / Cjp54 / virB8 / virB9 / virB10 / virB11 / virD41..3589835898


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10616.28 Da        Isoelectric Point: 9.5064

>T206515 WP_053868684.1 NZ_CP076837:30545-30814 [Campylobacter jejuni X]
MPYKITLSKKYKQKYKKANTKDRILIDEVVEKLSNDETLEEKYKDHALKGNYIGFRECHIKPDLLLVYRKNNDILELYLA
NLGNHNNIF

Download         Length: 270 bp

>T206515 NZ_CP102472:2517649-2518026 [Burkholderia multivorans]
ATGGGTATAAATTCATCGATGGTTCCGTACACCAAACCGCTCTACTGGCTCGGCTCGGCACGCAAGGACTTGAAAGCGAT
GCCCGAAGCGGTACGGGACACGTTCGGCTATGCGCTGTATCTGGCCCAGACGGGAGGAAAGCACGATCAGGCCAAGCCGT
TGAGGGGTTTCGGATCGGCCGGCGTACTCGAGGTCGTGGAGTCGGAGCACAGCGGCACGTACCGGGCGGTCTATACGGTG
AAACTCGGTGGCGCCGTCTATGTGCTGCACTGTTTCCAGAAGAAATCGTGCCGCGGTATCGCTACGCCGAAGCCGGACAT
CGAACTGGTTCGCGCGCGCCTGAGCGCCGCCGAAGCACACGCAAATGGAGAAAAGTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11186.76 Da        Isoelectric Point: 10.0400

>AT206515 WP_053868685.1 NZ_CP076837:30271-30555 [Campylobacter jejuni X]
MFDYSKYENASKKQLIHALTLAEKRAEKLNSQLKENNEFFKFLQKKLKKSFNAKKTKKAEQRRPELDEAIEDYKNGNVET
YANFEEYKKAMNAL

Download         Length: 285 bp

>AT206515 NZ_CP102472:2518026-2518349 [Burkholderia multivorans]
ATGATCGAAATCGAACGGGGCAGCGGGAACGTCTACGCGGATCTTGGCACGCCCGACGCCGAAGAAATGCGCGTCAAGGC
TCAACTCGCCGCCAAGATCGCGGAGATCATCAAGACTCGCAAATGGACGCAGCAGCACGCAGCACGATTGCTCGGCATGA
CGCAACCGAAGCTATCGAACATGCTGCGCGGGCAGTTTCGCGGCGTAAGCGAAGCGAAGATGCTCGACTGTCTCGCCAAG
CTCGGGCGCGATGTACAGATCGTCGTAGGACCGGACCGTCATTCGGAAACCGAAGGACACATCGAGGTCGTGTTCGCTGC
CTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A5T1CFM5

References