Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | TsdAT/- |
Location | 2094919..2095433 | Replicon | chromosome |
Accession | NZ_CP076823 | ||
Organism | Staphylococcus aureus strain ST59 |
Toxin (Protein)
Gene name | TsdT | Uniprot ID | T1YA99 |
Locus tag | KQY23_RS10235 | Protein ID | WP_000581792.1 |
Coordinates | 2094919..2095128 (-) | Length | 70 a.a. |
Antitoxin (Protein)
Gene name | TsdA | Uniprot ID | A0A0D1GBN9 |
Locus tag | KQY23_RS10240 | Protein ID | WP_000138934.1 |
Coordinates | 2095140..2095433 (-) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KQY23_RS10215 (2090427) | 2090427..2091785 | - | 1359 | WP_000611468.1 | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase | - |
KQY23_RS10220 (2091800) | 2091800..2092870 | - | 1071 | WP_000159641.1 | D-alanine--D-alanine ligase | - |
KQY23_RS10225 (2093188) | 2093188..2094390 | + | 1203 | WP_001109939.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
KQY23_RS10230 (2094654) | 2094654..2094791 | - | 138 | WP_000828354.1 | Lmo0850 family protein | - |
KQY23_RS10235 (2094919) | 2094919..2095128 | - | 210 | WP_000581792.1 | heavy metal-associated domain-containing protein | Toxin |
KQY23_RS10240 (2095140) | 2095140..2095433 | - | 294 | WP_000138934.1 | copper-sensing transcriptional repressor CsoR | Antitoxin |
KQY23_RS10245 (2095599) | 2095599..2097083 | + | 1485 | WP_057504585.1 | cardiolipin synthase | - |
KQY23_RS10250 (2097111) | 2097111..2097758 | + | 648 | WP_001187610.1 | HD domain-containing protein | - |
KQY23_RS10255 (2098573) | 2098573..2099445 | - | 873 | WP_000725802.1 | membrane protein insertase YidC | - |
KQY23_RS10260 (2099531) | 2099531..2100172 | - | 642 | WP_000483147.1 | thiamine phosphate synthase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 70 a.a. Molecular weight: 7843.77 Da Isoelectric Point: 4.1008
>T206507 WP_000581792.1 NZ_CP076823:c2095128-2094919 [Staphylococcus aureus]
MIHQNTIYTAGIETEEQVSQLTERISNMIGVHQVNINIIDGQVTVSYETPANLNSIEKEIYDEGYKIVF
MIHQNTIYTAGIETEEQVSQLTERISNMIGVHQVNINIIDGQVTVSYETPANLNSIEKEIYDEGYKIVF
Download Length: 210 bp
>T206507 NZ_CP102463:c2105194-2104877 [Burkholderia contaminans]
ATGCCCTACAGTGCGCCTACGTTCAGCATCCGGACCACCGACGTCTTCGACACCTGGTTTGCCGGCCTGCAGGATCGCGT
CGCGAAGCGCCGCATCCAGGCACGCATCGACCGCCTTTCGATGGGCAATCCGGGCGACTGGAAATCCGCCGGCTCGCCGG
TCGTCGAGATGCGGATCGACCACGGCCCGGGCTATCGCGTCTACTACGTCCGGCGCGGAACGATCTGGGTCATCCTGCTC
TGCGGTGGCGATAAATCGTCGCAACAGGCCGACATCCGCGCCGCGCACGCGATGCTCGCGCACCTCGACATGGAGTAA
ATGCCCTACAGTGCGCCTACGTTCAGCATCCGGACCACCGACGTCTTCGACACCTGGTTTGCCGGCCTGCAGGATCGCGT
CGCGAAGCGCCGCATCCAGGCACGCATCGACCGCCTTTCGATGGGCAATCCGGGCGACTGGAAATCCGCCGGCTCGCCGG
TCGTCGAGATGCGGATCGACCACGGCCCGGGCTATCGCGTCTACTACGTCCGGCGCGGAACGATCTGGGTCATCCTGCTC
TGCGGTGGCGATAAATCGTCGCAACAGGCCGACATCCGCGCCGCGCACGCGATGCTCGCGCACCTCGACATGGAGTAA
Antitoxin
Download Length: 98 a.a. Molecular weight: 11185.77 Da Isoelectric Point: 6.2243
>AT206507 WP_000138934.1 NZ_CP076823:c2095433-2095140 [Staphylococcus aureus]
MTEQDNAHHSEQIKTNLKSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVATKLLEQHMKSCIMNKVNQGAQ
EEAMEELLVTFQKLIKD
MTEQDNAHHSEQIKTNLKSRLNRIEGQVRAINRMIEEDVYCDDVLTQIRATRSALNSVATKLLEQHMKSCIMNKVNQGAQ
EEAMEELLVTFQKLIKD
Download Length: 294 bp
>AT206507 NZ_CP102463:c2104873-2104574 [Burkholderia contaminans]
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGATCATCTGAAAACCGAAGACGACATGGCCGACTACTTCGAAGC
GTGCCTGCAGGAAGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCGCGTGCACGCGGCATGTCGC
AGGTCGCGCGCGACGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAACCCCAGCTTCGGCACG
ATCCTGAAGGTCATCAAGGCGCTCGGCCTGCAACTGCACGGCTCGAAAGCGCACGCATGA
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGATCATCTGAAAACCGAAGACGACATGGCCGACTACTTCGAAGC
GTGCCTGCAGGAAGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCGCGTGCACGCGGCATGTCGC
AGGTCGCGCGCGACGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAACCCCAGCTTCGGCACG
ATCCTGAAGGTCATCAAGGCGCTCGGCCTGCAACTGCACGGCTCGAAAGCGCACGCATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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