Detailed information of TA system TA206473

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/-
• Location: 3537005..3537658
• Replicon: chromosome
• Accession: NZ_CP076739
• Organism: Acinetobacter baumannii strain X4-584

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: KRO88_RS17010
• Protein ID: WP_000607077.1
• Coordinates: 3537005..3537394 (-)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: V5V966
• Locus tag: KRO88_RS17015
• Protein ID: WP_001288210.1
• Coordinates: 3537401..3537658 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KRO88_RS16995 (KRO88_16875)	3532123..3534318	-	2196	WP_001158906.1	TRAP transporter large permease subunit	-
KRO88_RS17000 (KRO88_16880)	3534506..3535072	-	567	WP_000651538.1	rhombosortase	-
KRO88_RS17005 (KRO88_16885)	3535150..3536235	-	1086	WP_000049106.1	hypothetical protein	-
KRO88_RS17010 (KRO88_16890)	3537005..3537394	-	390	WP_000607077.1	membrane protein	Toxin
KRO88_RS17015 (KRO88_16895)	3537401..3537658	-	258	WP_001288210.1	succinate dehydrogenase assembly factor 2	Antitoxin
KRO88_RS17020 (KRO88_16900)	3537846..3539018	+	1173	WP_001190542.1	acyl-CoA dehydrogenase family protein	-
KRO88_RS17025 (KRO88_16905)	3539067..3540557	-	1491	WP_000415125.1	NAD(P)/FAD-dependent oxidoreductase	-
KRO88_RS17030 (KRO88_16910)	3540739..3541116	-	378	WP_001216380.1	50S ribosomal protein L17	-
KRO88_RS17035 (KRO88_16915)	3541135..3542142	-	1008	WP_000198631.1	DNA-directed RNA polymerase subunit alpha	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Flavinator of succinate dehydrogenase (10-82)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 15552.88 Da
• Isoelectric Point: 10.4313

>T206473 WP_000607077.1 NZ_CP076739:c3537394-3537005 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFISFIFFLKRPQLAQIAYLDKKLWSLAYKSQNTV
SRVKILKIIDCQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Nucleotide

• Length: 390 bp

>T206473 NZ_CP102438:801193-801603 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 10318.77 Da
• Isoelectric Point: 4.6150

>AT206473 WP_001288210.1 NZ_CP076739:c3537658-3537401 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Nucleotide

• Length: 258 bp

>AT206473 NZ_CP102438:800946-801212 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Structures

Antitoxin

• AlphaFold DB: A0A7U4BQM7