206463

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3267794..3268163 Replicon chromosome
Accession NZ_CP076726
Organism Xanthomonas arboricola pv. juglandis strain IVIA 2499

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag KP728_RS14060 Protein ID WP_016904515.1
Coordinates 3268029..3268163 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag KP728_RS14055 Protein ID WP_006451340.1
Coordinates 3267794..3267946 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP728_RS14030 (KP728_13945) 3263856..3264398 - 543 WP_016904520.1 GTPase -
KP728_RS14035 (KP728_13950) 3264395..3265312 - 918 WP_053046212.1 hypothetical protein -
KP728_RS14040 (KP728_13955) 3265407..3265766 - 360 WP_016904518.1 hypothetical protein -
KP728_RS14045 (KP728_13960) 3265830..3266282 - 453 WP_016904517.1 roadblock/LC7 domain-containing protein -
KP728_RS14050 (KP728_13965) 3266761..3267684 + 924 WP_026064823.1 arginase -
KP728_RS14055 (KP728_13970) 3267794..3267946 + 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
KP728_RS14060 (KP728_13975) 3268029..3268163 + 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
KP728_RS14065 (KP728_13980) 3268413..3268622 + 210 WP_016904514.1 CsbD family protein -
KP728_RS14070 (KP728_13985) 3268804..3270093 + 1290 WP_016904513.1 tryptophan--tRNA ligase -
KP728_RS14075 (KP728_13990) 3270151..3271095 + 945 WP_016904512.1 MBL fold metallo-hydrolase -
KP728_RS14080 (KP728_13995) 3271422..3272441 + 1020 WP_047124271.1 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T206463 WP_016904515.1 NZ_CP076726:3268029-3268163 [Xanthomonas arboricola pv. juglandis]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T206463 NZ_CP102435:c4577227-4576943 [Klebsiella pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGGCCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT206463 WP_006451340.1 NZ_CP076726:3267794-3267946 [Xanthomonas arboricola pv. juglandis]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT206463 NZ_CP102435:c4577459-4577217 [Klebsiella pneumoniae]
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGCCGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCGGGGGTTAAGGTGAGTCTGGATGACCTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References