206459

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4887439..4887808 Replicon chromosome
Accession NZ_CP076725
Organism Xanthomonas arboricola pv. juglandis strain IVIA 1317

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag KP727_RS20955 Protein ID WP_016904515.1
Coordinates 4887439..4887573 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag KP727_RS20960 Protein ID WP_006451340.1
Coordinates 4887656..4887808 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP727_RS20935 (KP727_20850) 4883161..4884180 - 1020 WP_047124271.1 IS5 family transposase -
KP727_RS20940 (KP727_20855) 4884507..4885451 - 945 WP_016904512.1 MBL fold metallo-hydrolase -
KP727_RS20945 (KP727_20860) 4885509..4886798 - 1290 WP_016904513.1 tryptophan--tRNA ligase -
KP727_RS20950 (KP727_20865) 4886980..4887189 - 210 WP_016904514.1 CsbD family protein -
KP727_RS20955 (KP727_20870) 4887439..4887573 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
KP727_RS20960 (KP727_20875) 4887656..4887808 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
KP727_RS20965 (KP727_20880) 4887918..4888841 - 924 WP_026064823.1 arginase -
KP727_RS20970 (KP727_20885) 4889320..4889772 + 453 WP_016904517.1 roadblock/LC7 domain-containing protein -
KP727_RS20975 (KP727_20890) 4889836..4890195 + 360 WP_016904518.1 hypothetical protein -
KP727_RS20980 (KP727_20895) 4890290..4891207 + 918 WP_053046212.1 hypothetical protein -
KP727_RS20985 (KP727_20900) 4891204..4891746 + 543 WP_016904520.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T206459 WP_016904515.1 NZ_CP076725:c4887573-4887439 [Xanthomonas arboricola pv. juglandis]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T206459 NZ_CP102435:c3918068-3917661 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCGTGC
GCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCCGAA
TGGGAAATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGGACA
GCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGGCGC
AGGAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT206459 WP_006451340.1 NZ_CP076725:c4887808-4887656 [Xanthomonas arboricola pv. juglandis]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT206459 NZ_CP102435:c3918315-3918049 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References