Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1376621..1377214 Replicon chromosome
Accession NZ_CP076724
Organism Geomonas nitrogeniifigens strain RG29

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag KP005_RS06060 Protein ID WP_216791141.1
Coordinates 1376924..1377214 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag KP005_RS06055 Protein ID WP_216498656.1
Coordinates 1376621..1376914 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP005_RS06035 (KP005_06035) 1372864..1373085 - 222 WP_216498652.1 NifU family protein -
KP005_RS06040 (KP005_06040) 1373191..1374591 - 1401 WP_216498653.1 aspartate ammonia-lyase -
KP005_RS06045 (KP005_06045) 1374652..1375284 - 633 WP_239027621.1 HAD family hydrolase -
KP005_RS06050 (KP005_06050) 1375281..1376441 - 1161 WP_216791139.1 SAM-dependent methyltransferase -
KP005_RS06055 (KP005_06055) 1376621..1376914 - 294 WP_216498656.1 putative addiction module antidote protein Antitoxin
KP005_RS06060 (KP005_06060) 1376924..1377214 - 291 WP_216791141.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KP005_RS06065 (KP005_06065) 1377318..1378322 - 1005 WP_216498658.1 transcriptional regulator -
KP005_RS06070 (KP005_06070) 1378319..1379749 - 1431 WP_216498659.1 DEAD/DEAH box helicase -
KP005_RS06075 (KP005_06075) 1380274..1380897 + 624 WP_216498660.1 tRNA (guanosine(46)-N7)-methyltransferase TrmB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Uncharacterized protein HI1420

(6-94)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10785.48 Da        Isoelectric Point: 10.3368

>T206457 WP_216791141.1 NZ_CP076724:c1377214-1376924 [Geomonas nitrogeniifigens]
MPEIRKTDTFKKWLDNLRDLDAKARVLVRIERLACGNAGDIKTVGDGVSELRIDYGPGYRVYFTKRGNQVIILLAGGDKS
SQSRDIKRALHLALNL

Download         Length: 291 bp

>T206457 NZ_CP102435:2125969-2127291 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCTGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10482.01 Da        Isoelectric Point: 6.4655

>AT206457 WP_216498656.1 NZ_CP076724:c1376914-1376621 [Geomonas nitrogeniifigens]
MTKTTTSRYDVAEHLRTPEEMAAYLEACLEEANGDAAFIAKALGDIARAKGMSQVAREAGLSRESLYKALSGERVPSFDT
ILKIIAALGLKLHAEAR

Download         Length: 294 bp

>AT206457 NZ_CP102435:2125703-2125969 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References