Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2092639..2092910 Replicon chromosome
Accession NZ_CP076709
Organism Escherichia coli O158:H23 strain CFIAFB20140388

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2092677..2092780 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2092639..2092910 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQ220_RS10020 2089795..2091234 + 1440 WP_024165618.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KQ220_RS10025 2091352..2091588 + 237 WP_001295499.1 YebV family protein -
KQ220_RS10030 2091693..2091884 + 192 WP_001296140.1 YebW family protein -
KQ220_RS10035 2091885..2092542 - 658 Protein_1973 protein-serine/threonine phosphatase -
- 2092639..2092910 + 272 - - Antitoxin
- 2092677..2092780 - 104 - - Toxin
KQ220_RS10040 2092938..2093279 - 342 WP_000976472.1 YebY family protein -
KQ220_RS10045 2093292..2094164 - 873 WP_112004944.1 copper homeostasis membrane protein CopD -
KQ220_RS10050 2094168..2094542 - 375 WP_000168745.1 CopC domain-containing protein YobA -
KQ220_RS10055 2094681..2094911 + 231 WP_000916763.1 DNA polymerase III subunit theta -
KQ220_RS10060 2095013..2095669 + 657 WP_216781486.1 carbon-nitrogen hydrolase family protein YobB -
KQ220_RS10065 2095693..2096355 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2076798..2116694 39896


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T206421 NZ_CP076709:c2092780-2092677 [Escherichia coli O158:H23]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT206421 NZ_CP076709:2092639-2092910 [Escherichia coli O158:H23]
AAAGTCAGCGAAAGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References