Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 567961..568229 Replicon chromosome
Accession NZ_CP076706
Organism Escherichia coli O170:H18 strain CFIAFB20120266

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 567999..568101 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 567961..568229 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQ217_RS02865 565118..566557 + 1440 WP_024190479.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
KQ217_RS02870 566675..566911 + 237 WP_001295499.1 YebV family protein -
KQ217_RS02875 567016..567207 + 192 WP_001317886.1 YebW family protein -
KQ217_RS02880 567208..567864 - 657 WP_001357783.1 protein-serine/threonine phosphatase -
- 567961..568229 + 269 - - Antitoxin
- 567999..568101 - 103 - - Toxin
KQ217_RS02885 568259..568600 - 342 WP_000976472.1 YebY family protein -
KQ217_RS02890 568613..569485 - 873 WP_000879311.1 copper homeostasis membrane protein CopD -
KQ217_RS02895 569489..569863 - 375 WP_000168747.1 CopC domain-containing protein YobA -
KQ217_RS02900 570002..570232 + 231 WP_000916763.1 DNA polymerase III subunit theta -
KQ217_RS02905 570334..570990 + 657 WP_000011646.1 carbon-nitrogen hydrolase family protein YobB -
KQ217_RS02910 571014..571676 + 663 WP_000944249.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T206381 NZ_CP076706:c568101-567999 [Escherichia coli O170:H18]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT206381 NZ_CP076706:567961-568229 [Escherichia coli O170:H18]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References