Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1989787..1990058 Replicon chromosome
Accession NZ_CP076704
Organism Escherichia coli O8:H28 strain BMH-17-0027

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1989917..1990020 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1989787..1990058 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQ221_RS09565 1986342..1987004 - 663 WP_000944256.1 exodeoxyribonuclease X -
KQ221_RS09570 1987028..1987684 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
KQ221_RS09575 1987786..1988016 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KQ221_RS09580 1988155..1988529 + 375 WP_000204699.1 CopC domain-containing protein YobA -
KQ221_RS09585 1988533..1989405 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
KQ221_RS09590 1989418..1989759 + 342 WP_000976492.1 YebY family protein -
- 1989787..1990058 - 272 - - Antitoxin
- 1989917..1990020 + 104 - - Toxin
KQ221_RS09595 1990155..1990811 + 657 WP_000812723.1 protein-serine/threonine phosphatase -
KQ221_RS09600 1990812..1991003 - 192 WP_001338167.1 YebW family protein -
KQ221_RS09605 1991108..1991344 - 237 WP_001295499.1 YebV family protein -
KQ221_RS09610 1991462..1992901 - 1440 WP_001352399.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T206353 NZ_CP076704:1989917-1990020 [Escherichia coli O8:H28]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT206353 NZ_CP076704:c1990058-1989787 [Escherichia coli O8:H28]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAATAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References