206344

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2678607..2678976 Replicon chromosome
Accession NZ_CP076701
Organism Xanthomonas arboricola pv. pruni strain CITA 33

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag KQR53_RS11565 Protein ID WP_016904515.1
Coordinates 2678842..2678976 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag KQR53_RS11560 Protein ID WP_006451340.1
Coordinates 2678607..2678759 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQR53_RS11535 (KQR53_11475) 2674673..2675215 - 543 WP_016904520.1 GTPase -
KQR53_RS11540 (KQR53_11480) 2675212..2676129 - 918 WP_039512632.1 hypothetical protein -
KQR53_RS11545 (KQR53_11485) 2676223..2676582 - 360 WP_039512630.1 hypothetical protein -
KQR53_RS11550 (KQR53_11490) 2676646..2677098 - 453 WP_039512628.1 roadblock/LC7 domain-containing protein -
KQR53_RS11555 (KQR53_11495) 2677574..2678497 + 924 WP_039512664.1 arginase -
KQR53_RS11560 (KQR53_11500) 2678607..2678759 + 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
KQR53_RS11565 (KQR53_11505) 2678842..2678976 + 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
KQR53_RS11570 (KQR53_11510) 2679227..2679436 + 210 WP_039512625.1 CsbD family protein -
KQR53_RS11575 (KQR53_11515) 2679618..2680907 + 1290 WP_039814994.1 tryptophan--tRNA ligase -
KQR53_RS11580 (KQR53_11520) 2680965..2681909 + 945 WP_039512622.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T206344 WP_016904515.1 NZ_CP076701:2678842-2678976 [Xanthomonas arboricola pv. pruni]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T206344 NZ_CP102374:c3971411-3971229 [Pseudomonas sp. T8]
ATGCGCAGTCGGGAACTGATCAGGATGATCGAGGAGGACGGGTGGTATCTGATCGCGGTCAAAGGCAGTCATCACCAATA
CAAGCATCTGCACAAGCCGGGACGGGTCACTATCCCTCACCCGGATGCGGATCTGCCCAGGGGCACGATCCACAGCATCT
TGAAACAGGCGGGCCTGAAATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT206344 WP_006451340.1 NZ_CP076701:2678607-2678759 [Xanthomonas arboricola pv. pruni]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT206344 NZ_CP102374:c3971199-3970798 [Pseudomonas sp. T8]
ATGAAATTCCCGGTCGTGCTGCACAAGGATGCCGACTCCGGATATGGAGTGATCGTCCCCGATGTGCCGGGCTGTTTTTC
CGCCGGTCATACCGCTGCGCAAGCCTTCGAGAATGTGAAAGAGGCCCTGTCGCTGCATTACGAAGGCCTGGTCGCCGATG
GTGAGCCGCTGCCCCAGGTGCATGAGGTCGACGTGCATATCGACAATCCTGATTACGCCGGTGGCGTGTGGGGGGTGATC
GAGTTCGACATCACGCCTTACTTCGGCAAGGCGGTGCGTTTCAATGCGACGTTGCCGGAGCAACTGTTGGAGCGCATCGA
CCAGACGGTGAAGCGCGACCAGCGCTACCGTTCGCGCTCGGGCTTTCTCGCGGCAGCGGCATTGCGCGAACTCTCCGCCT
AG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References