Detailed information of TA system TA206342

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 2206276..2206820
• Replicon: chromosome
• Accession: NZ_CP076701
• Organism: Xanthomonas arboricola pv. pruni strain CITA 33

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KQR53_RS09695
• Protein ID: WP_228960823.1
• Coordinates: 2206276..2206545 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A2N7V9L6
• Locus tag: KQR53_RS09700
• Protein ID: WP_016902922.1
• Coordinates: 2206563..2206820 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KQR53_RS09665 (KQR53_09615)	2201547..2202440	+	894	WP_043087408.1	LysR family transcriptional regulator	-
KQR53_RS09670 (KQR53_09620)	2202451..2203164	-	714	WP_039511101.1	hypothetical protein	-
KQR53_RS09675 (KQR53_09625)	2203622..2204713	+	1092	WP_039511112.1	ATP-grasp fold amidoligase family protein	-
KQR53_RS09680 (KQR53_09630)	2204873..2205079	-	207	WP_223571151.1	hypothetical protein	-
KQR53_RS09685 (KQR53_09635)	2205115..2205465	+	351	WP_236674533.1	helix-turn-helix domain-containing protein	-
KQR53_RS09690 (KQR53_09640)	2205636..2206157	+	522	WP_051633992.1	hypothetical protein	-
KQR53_RS09695 (KQR53_09645)	2206276..2206545	-	270	WP_228960823.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KQR53_RS09700 (KQR53_09650)	2206563..2206820	-	258	WP_016902922.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
KQR53_RS09705 (KQR53_09655)	2206876..2207538	-	663	WP_039511099.1	hemolysin III family protein	-
KQR53_RS09710 (KQR53_09660)	2207712..2210207	+	2496	WP_043087409.1	DEAD/DEAH box helicase	-
KQR53_RS09715 (KQR53_09665)	2210204..2211712	+	1509	WP_043087410.1	ribonuclease H-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2196528..2206820	10292

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-80)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10221.75 Da
• Isoelectric Point: 10.1539

>T206342 WP_228960823.1 NZ_CP076701:c2206545-2206276 [Xanthomonas arboricola pv. pruni]
VADLDAIADYIALEDAAAAAALVRRVFAHVEQLAEHPESGSRPQELKRSRYRQIVEPPCRVFYRVDGQRVVVVHVMRSER
LLRKNRLSR

Nucleotide

• Length: 270 bp

>T206342 NZ_CP102374:c3752406-3752110 [Pseudomonas sp. T8]
ATGCATATCATCACCGCCAAACGAATCTGGGAGGCCAAGAGCCGCTGGCCACAATCGGCCAATGCGCTGGAGACCTGGTA
CAGAAAAGTCAAAAGCCTCAATCCGGCCGATTTTGCAGCCATCAAGGCAGTATTTCCGGCCACCGACAAAGTGGGGGCGT
TTCACGTCTTCGATATTGGCGGCAACAAGTTACGAATCATCGCTGTGGTGCGTTATGAGGTGCGACGTCTCTATATCAGG
CACGTGCTGGACCATCACGAATACGACAAGGGCAGGTGGAAGGAGGAGACCAGATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9704.23 Da
• Isoelectric Point: 8.6056

>AT206342 WP_016902922.1 NZ_CP076701:c2206820-2206563 [Xanthomonas arboricola pv. pruni]
MRTELVTTLKRQATELLADVERDKEPILITQHGLPSAYLVDVASYERMQQRMAILEGIARGEMAVAEGRSLSHEQAKQRL
ARWLK

Nucleotide

• Length: 258 bp

>AT206342 NZ_CP102374:c3752113-3751712 [Pseudomonas sp. T8]
ATGAACGTTCTGGTGAAGCAGGCGGCGGATCATTGGCATTTCGTGGCCCCTGTGTTGCGTAAACCCAATACTGAAGCCGA
TTACGATGCATTGGTCGCGGCGCTGGATGAACTGCTGGATCTCATGGGAGAGGACGAGAACCATCCAGTGACTTCGCTGG
TGGACATCATCGGCGATTGGATCGAAGCCTACGACGAAGAGCATCGACCGATGCCGATAGCCAGTGGCGTTGACGTCTTG
CGCTCCCTGATGCGCGAACACGGCCTGACCCAGAGTGATTTGCCAGGCGTGGGTGCGCAGTCGGTGGTTTCGGAAGTACT
GAGCGGCAAGCGCCAGCTCAACCTGCGACAGATCCGCTGGCTGGCCGAGCGCTTCGGTGTTTCGGCCGAGGTATTTATCT
GA

Structures

Antitoxin

• AlphaFold DB: A0A2N7V9L6