206200

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 4378742..4379456 Replicon chromosome
Accession NZ_CP076679
Organism Rhodopseudomonas palustris strain VNW64

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag KQX61_RS20335 Protein ID WP_012497200.1
Coordinates 4379073..4379456 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag KQX61_RS20330 Protein ID WP_264053097.1
Coordinates 4378742..4379065 (-) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQX61_RS20305 (KQX61_20210) 4375023..4375724 - 702 WP_264053095.1 phosphoribosylformylglycinamidine synthase subunit PurQ -
KQX61_RS20310 (KQX61_20215) 4375721..4375975 - 255 WP_264053096.1 DUF1664 domain-containing protein -
KQX61_RS20315 (KQX61_20220) 4376048..4376293 - 246 WP_011159358.1 phosphoribosylformylglycinamidine synthase subunit PurS -
KQX61_RS20320 (KQX61_20225) 4376475..4377242 - 768 WP_199851757.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
KQX61_RS20325 (KQX61_20230) 4377540..4377863 + 324 WP_107345553.1 DUF1476 domain-containing protein -
KQX61_RS20330 (KQX61_20235) 4378742..4379065 - 324 WP_264053097.1 helix-turn-helix transcriptional regulator Antitoxin
KQX61_RS20335 (KQX61_20240) 4379073..4379456 - 384 WP_012497200.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KQX61_RS20340 (KQX61_20245) 4379565..4380383 - 819 WP_264053098.1 isocitrate lyase/phosphoenolpyruvate mutase family protein -
KQX61_RS20345 (KQX61_20250) 4380796..4381137 + 342 WP_264053099.1 type II toxin-antitoxin system RelE/ParE family toxin -
KQX61_RS20350 (KQX61_20255) 4381130..4381453 + 324 WP_114358812.1 transcriptional regulator -
KQX61_RS20355 (KQX61_20260) 4381742..4381981 + 240 WP_264053101.1 hypothetical protein -
KQX61_RS20360 (KQX61_20265) 4382111..4382965 - 855 WP_264053102.1 hypothetical protein -
KQX61_RS20365 (KQX61_20270) 4382996..4383478 - 483 WP_264053103.1 transcription elongation factor GreA -
KQX61_RS20370 (KQX61_20275) 4383539..4384027 - 489 WP_264053104.1 mismatch-specific DNA-glycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4372191..4382965 10774


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(20-112)

Antitoxin

HigA2-like, helix-turn-helix domain

(12-91)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14384.36 Da        Isoelectric Point: 10.1303

>T206200 WP_012497200.1 NZ_CP076679:c4379456-4379073 [Rhodopseudomonas palustris]
MRPRLVSGEKPLHWVGSSKDDLCAFPLPVQREIGNALGLAQFGGKHPRAKPWKGEGPGVFEMVDDFDGDTYRAVYTVRFR
HAVYVLHAFQKKSPRGIRTARGDIELIARRLKLARQDDEARDGENDR

Download         Length: 384 bp

>T206200 NZ_CP102190:c40548-40273 [Klebsiella pneumoniae]
ATGGAACTGAAGTGGACCAGTAAGGCGCTTTCTGATTTGGCGCGGTTATATGATTTTCTGGTGCTGGCCAGTAAACCTGC
GGCCGCCAGAACGGTGCAATCCCTGACACAGGCACCGGTCATTCTGTTAACTCATCCACGTATGGGAGAACAGTTGTTTC
AGTTTGAACCCAGGGAGGTCAGACGGATTTTTGCTGGCGAGTACGAAATCCGTTACGAACTTAATGGCCAGACTATTTAT
GTATTGCGCCTGTGGCACACACGAGAAAACAGGTAG

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11710.55 Da        Isoelectric Point: 10.7003

>AT206200 WP_264053097.1 NZ_CP076679:c4379065-4378742 [Rhodopseudomonas palustris]
MAAEITRGSGNVFADLGMADAEERQTKLRLTYALNAVIDRARLSQAAAAERLGINQPKVSALRNYKLEGFSVERLMTLLN
ALDQDIEIVIRKKPRSRAAARISVVAA

Download         Length: 324 bp

>AT206200 NZ_CP102190:c40832-40548 [Klebsiella pneumoniae]
ATGCAAATGAAAAACAATACCGCACAGGCAACAAAAGTCATTACCGCGCATGTGCCATTACCTATGGCTGATAAAGTCGA
CCAGATGGCCGCCAGGCTGGAACGCTCCCGGGGCTGGGTTATCAAACAGGCGCTTTCTGCATGGCTTGCCCAGGAGGAGG
AGCGTAATCGCCTGACGCTGGAAGCCCTGGACGATGTGACATCCGGACAGGTTATCGACCATCAGGCTGTACAGGCCTGG
GCGGACAGCCTCAGTACTGACAATCCGTTACCGGTGCCACGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References