Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4265426..4266060 Replicon chromosome
Accession NZ_CP076677
Organism Rhodopseudomonas palustris strain PP803

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KQX63_RS19670 Protein ID WP_263989344.1
Coordinates 4265426..4265827 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KQX63_RS19675 Protein ID WP_107345563.1
Coordinates 4265824..4266060 (-) Length 79 a.a.

Genomic Context

KQX63_RS19645KQX63_RS19650KQX63_RS19685KQX63_RS19690KQX63_RS19695KQX63_RS19630KQX63_RS19635KQX63_RS19640KQX63_RS19655KQX63_RS19660KQX63_RS19665KQX63_RS19670KQX63_RS19675KQX63_RS19680
Location: 4262814..4263053 (240 bp)
Type: Others
Protein ID: WP_263989338.1
Location: 4263050..4263775 (726 bp)
Type: Others
Protein ID: WP_263989340.1
Location: 4267711..4268934 (1224 bp)
Type: Others
Protein ID: WP_107345565.1
Location: 4269062..4269394 (333 bp)
Type: Others
Protein ID: WP_107345566.1
Location: 4269525..4270385 (861 bp)
Type: Others
Protein ID: WP_263989346.1
Location: 4260715..4261065 (351 bp)
Type: Others
Protein ID: WP_263989336.1
Location: 4261046..4261429 (384 bp)
Type: Others
Protein ID: WP_263991757.1
Location: 4261538..4262356 (819 bp)
Type: Others
Protein ID: WP_263989337.1
Location: 4263825..4264310 (486 bp)
Type: Others
Protein ID: WP_263989341.1
Location: 4264371..4264907 (537 bp)
Type: Others
Protein ID: WP_263989342.1
Location: 4264908..4265309 (402 bp)
Type: Others
Protein ID: WP_263989343.1
Location: 4265426..4265827 (402 bp)
Type: Toxin
Protein ID: WP_263989344.1
Location: 4265824..4266060 (237 bp)
Type: Antitoxin
Protein ID: WP_107345563.1
Location: 4266125..4267321 (1197 bp)
Type: Others
Protein ID: WP_263989345.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KQX63_RS19630 (KQX63_19550)4260715..4261065-351WP_263989336.1helix-turn-helix transcriptional regulator-
KQX63_RS19635 (KQX63_19555)4261046..4261429-384WP_263991757.1type II toxin-antitoxin system RelE/ParE family toxin-
KQX63_RS19640 (KQX63_19560)4261538..4262356-819WP_263989337.1isocitrate lyase/phosphoenolpyruvate mutase family protein-
KQX63_RS19645 (KQX63_19565)4262814..4263053+240WP_263989338.1hypothetical protein-
KQX63_RS19650 (KQX63_19570)4263050..4263775+726WP_263989340.1Fic family protein-
KQX63_RS19655 (KQX63_19575)4263825..4264310-486WP_263989341.1transcription elongation factor GreA-
KQX63_RS19660 (KQX63_19580)4264371..4264907-537WP_263989342.1mismatch-specific DNA-glycosylase-
KQX63_RS19665 (KQX63_19585)4264908..4265309-402WP_263989343.1DUF2147 domain-containing protein-
KQX63_RS19670 (KQX63_19590)4265426..4265827-402WP_263989344.1type II toxin-antitoxin system VapC family toxinToxin
KQX63_RS19675 (KQX63_19595)4265824..4266060-237WP_107345563.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
KQX63_RS19680 (KQX63_19600)4266125..4267321-1197WP_263989345.1TrmJ/YjtD family RNA methyltransferase-
KQX63_RS19685 (KQX63_19605)4267711..4268934+1224WP_107345565.1NADP-dependent isocitrate dehydrogenase-
KQX63_RS19690 (KQX63_19610)4269062..4269394+333WP_107345566.1YnfA family protein-
KQX63_RS19695 (KQX63_19615)4269525..4270385+861WP_263989346.1AraC family transcriptional regulator-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideGenomic island--4259554..427448714933


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(10-57)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 13908.88 Da        Isoelectric Point: 4.5201

>T206196 WP_263989344.1 NZ_CP076677:c4265827-4265426 [Rhodopseudomonas palustris]
VTRYMLDTSILSDLIRNPHGAAVRCIAEVGEGNVCTSIIVAAELRYGCAKSGSVKLTKAVADLLEEIDVLPFEPPADEVY
GAIRSSLEAAGTPIGSNDLLIAAHAKSLGATIVTANTQEFGRVQGLAVENWVA

Download         Length: 402 bp

>T206196 NZ_CP102187:193445-193915 [Klebsiella pneumoniae]
GTGATCCTCTACAGGCTGACGAAAACAAAGTATCTTTCTACGGCCTGGACCGGATATGGTGCGAAAGAGGCTGGTGGGCG
TTGGAATAGCGTGGGGGTGTCAATGGTATATGTCTCCGAAACGGCATCACTAACGATGCTGGAGACGCTGGTACACCTGC
ATGCGGCACAGATAATGGACTCTTTCACGCTACTGAGTATCGATGTGCCTGATGAACTGATCCAAAGCGCAAACATGGAT
GAATTACCGGGCAACTGGGCTGATGAGGATGCGCCTCAGGAACTGGCTGATTACGGAGATGCCTGGTCATTTACCAGGAG
CTCGGTTGCACTGCGTGTTCCCTCAGCCTTATCGCCGGTAGAGTTCAACTATCTGTTAAATCCTGAGCACCCTGAGTTTT
ACGGGATCGTGCAGAAGGCTCAACAGATACCGTTCCGGTTTGATAGTCGTCTTAAACCTGACAGGAAGTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8953.47 Da        Isoelectric Point: 8.9339

>AT206196 WP_107345563.1 NZ_CP076677:c4266060-4265824 [Rhodopseudomonas palustris]
MTDRRHVRLFRNGRNQAVRIPVEFEMPGNEAIMHREGDRLVIEPVRKRGLIALLKSMTPLDEPFPVIDDPAPAPEKVL

Download         Length: 237 bp

>AT206196 NZ_CP102187:193005-193448 [Klebsiella pneumoniae]
ATGAAAACATTTAGTTTGTCCTCAACTCCAGCCAGACCACAGCGCCTCTGGCAGGTTGCCGGGTTAAATAATGCTGATGG
CGTAGCGCTTCTGGGCCAAATCAATGAAGGCCTGGACGGGAAGGTGGCGAATCGGATCACTGACTGGGCCAGAATAACCC
AGAATGACCTGAGAAAAATGTCCGGTATCCCGTCGACCACGTTTAGCCGCAGTGTGAAGGCACGTTTTAACCCGGAACAA
AGTGAACGTCTGGTACGGATTATCCGCGTCATTGATCGGGCGGTAGATTTGTTTGAAGGCGACAAGGAAGCCGCACAGAA
GTGGTTGAACGAACCTAACCGGGCATTGAGCTGGAAAGTGCCAGCAGACCTGATGGCATCCGAGACAGGAGCGTATGAGG
TCATTAAGCTGATTACGCGTCTGGAGCATGGGGTGTACTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References