Detailed information of TA system TA206195

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-MazE
• Location: 3867033..3867664
• Replicon: chromosome
• Accession: NZ_CP076677
• Organism: Rhodopseudomonas palustris strain PP803

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: KQX63_RS17825
• Protein ID: WP_263989068.1
• Coordinates: 3867033..3867437 (-)
• Length: 135 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: KQX63_RS17830
• Protein ID: WP_107357567.1
• Coordinates: 3867434..3867664 (-)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KQX63_RS17810 (KQX63_17730)	3862051..3862293	-	243	WP_011159021.1	hypothetical protein	-
KQX63_RS17815 (KQX63_17735)	3862630..3863853	+	1224	WP_263989066.1	efflux RND transporter periplasmic adaptor subunit	-
KQX63_RS17820 (KQX63_17740)	3863856..3866990	+	3135	WP_263989067.1	multidrug efflux RND transporter permease subunit	-
KQX63_RS17825 (KQX63_17745)	3867033..3867437	-	405	WP_263989068.1	PIN domain-containing protein	Toxin
KQX63_RS17830 (KQX63_17750)	3867434..3867664	-	231	WP_107357567.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
KQX63_RS17840 (KQX63_17760)	3868166..3870817	-	2652	WP_263989069.1	DEAD/DEAH box helicase family protein	-
KQX63_RS17845 (KQX63_17765)	3870827..3872398	-	1572	WP_263989070.1	site-specific DNA-methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-114)

Antitoxin

• SpoVT-AbrB domain (5-39)

Sequences

Toxin

Protein

• Length: 135 a.a.
• Molecular weight: 14546.51 Da
• Isoelectric Point: 4.8999

>T206195 WP_263989068.1 NZ_CP076677:c3867437-3867033 [Rhodopseudomonas palustris]
VTAFFDTNILVYAQETGAKADRARAVLGGGGRLSVQVLNEFTVVVQRKFGRGWREIAEAIDDALAVSGPPLPLTQDLHVA
ARVLAETCKLSFYDALIVAAAQEAGCEVLYSEDLQHGRSFGTLRVENPFLENPR

Nucleotide

• Length: 405 bp

>T206195 NZ_CP102187:153384-153827 [Klebsiella pneumoniae]
ATGAAGAAAACCTGGATGCTCGACACTAACATCTGCTCGTTCATCATGCGCGAGCAGCCGGCAGCGGTGCTGAAGCGCCT
GGAACAGGCGGTGCTGCGCGGTGATCGCATCGTGGTCTCGGCCGTGACGTATGCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGCCATATTCAGCTGGTCGACGCGTTCTGCGCGCGCCTCGATGCCATCCTGCCCTGGGACCGGGCC
GCGGTGGACGCCACGACGGACATCCGGGTGGCGCTGCGCCTCGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
TGGGCACGCTATCGCGGCCGGCGCCGTCCTAGTGACGAACAATGTGAGAGAGTTTGAGCGGGTGCCGGGTCTGGTGCTGG
AAGACTGGGTGAAGAAAGCCGCTCTCTGCAGGGTAATTTCTTGA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8939.19 Da
• Isoelectric Point: 6.3983

>AT206195 WP_107357567.1 NZ_CP076677:c3867664-3867434 [Rhodopseudomonas palustris]
MKVSRWGNSLAVRLPNALVDKLDLKEGDELNVVDVVERTVVVEKEDRRKAALERMAERKWKLPEGYRFDRDEANER

Nucleotide

• Length: 231 bp

>AT206195 NZ_CP102187:153157-153387 [Klebsiella pneumoniae]
ATGCGCACAGTTTCGATATTTAAAAACGGCAATAACCGCGCCATCCGTCTGCCCCGGGACCTGGATTTTGACGGCGTCAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGCTGG
ACAGGGCCGCTCCGGACTTTATGGCGGAGCGTGAGGATGTGGTCAGCGATGAAGGACGCTTTGAGCCATGA