Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 3590632..3591321 Replicon chromosome
Accession NZ_CP076677
Organism Rhodopseudomonas palustris strain PP803

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag KQX63_RS16490 Protein ID WP_047308695.1
Coordinates 3590899..3591321 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag KQX63_RS16485 Protein ID WP_047308694.1
Coordinates 3590632..3590886 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQX63_RS16465 (KQX63_16390) 3586007..3586792 - 786 WP_263988880.1 ATP12 family protein -
KQX63_RS16470 (KQX63_16395) 3586810..3587169 - 360 WP_263988882.1 hypothetical protein -
KQX63_RS16475 (KQX63_16400) 3587210..3588505 - 1296 WP_263988883.1 RluA family pseudouridine synthase -
KQX63_RS16480 (KQX63_16405) 3589202..3590140 + 939 WP_263988884.1 hypothetical protein -
KQX63_RS16485 (KQX63_16410) 3590632..3590886 + 255 WP_047308694.1 plasmid stabilization protein Antitoxin
KQX63_RS16490 (KQX63_16415) 3590899..3591321 + 423 WP_047308695.1 type II toxin-antitoxin system VapC family toxin Toxin
KQX63_RS16495 (KQX63_16420) 3591483..3592058 - 576 WP_263988885.1 HXXEE domain-containing protein -
KQX63_RS16500 (KQX63_16425) 3592527..3593501 + 975 WP_263988886.1 OmpA family protein -
KQX63_RS16505 (KQX63_16430) 3593712..3594389 + 678 WP_263988887.1 nitroreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14812.84 Da        Isoelectric Point: 4.8187

>T206194 WP_047308695.1 NZ_CP076677:3590899-3591321 [Rhodopseudomonas palustris]
MIVLDTNVVSEAMTREPHPRVREWLNAQSAETLFLSSITVAELLFGVSVLPAGKRKNALGAALDDVLDVFATRILPFDTP
AAQRYADLAVKARAAGKGFPTPDGYIAAIATAHGFAVASRDASAFDAAGLTVIDPWTTND

Download         Length: 423 bp

>T206194 NZ_CP102187:17158-17469 [Klebsiella pneumoniae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTAAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9436.80 Da        Isoelectric Point: 6.4733

>AT206194 WP_047308694.1 NZ_CP076677:3590632-3590886 [Rhodopseudomonas palustris]
MVAVTIRNLSEEAHRALKVRAAQHNRSAEAEMRAILEAAVRPEGRLLLGTALQEIGQKYDITNADIEAIEQVRDKRPAEP
MKFE

Download         Length: 255 bp

>AT206194 NZ_CP102187:17466-17885 [Klebsiella pneumoniae]
ATGATTACCGACACTGCAAAAGCCATTGAAGCAACCAAACAACTCGTAGCTGCCGTCCCCTTCCTAGGGGGCAGTTCTTC
CGAGAGCGATTACCGCGAAGCGATGGAGCTGGTGGATTATCTGATCGAGAACGACGACGAGAACCCACTTATTGACTTCC
TGGCGAGTAAGATTGCCGACTATGAAGATAACAGCCCTCGTTTCGCTGAGTTCAACAAAGCTATTGCTGAAATACCAGTC
GGCGTTGCACTTCTGCGAACCCTGATTGACCAGCACAAGCTGTCTTATTCAGACCTTAAGGATGAGATCGGATCTAAATC
ATTGGTCAGCCAAATCCTGTCAGGGCAGCGCTCTTTGACCATCACTCACATAAAAGCTCTTTCCGCGCGCTTCGGTGTAA
AACCTGAGTGGTTCCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References