Detailed information of TA system TA206190

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ataRT/DUF1778(antitoxin)
• Location: 3888823..3889682
• Replicon: chromosome
• Accession: NZ_CP076676
• Organism: Rhodopseudomonas palustris strain TLS06

Toxin (Protein)

• Gene name: ataT
• Uniprot ID: -
• Locus tag: KQX62_RS18095
• Protein ID: WP_264074148.1
• Coordinates: 3888823..3889356 (-)
• Length: 178 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: KQX62_RS18100
• Protein ID: WP_264076666.1
• Coordinates: 3889344..3889682 (-)
• Length: 113 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KQX62_RS18075 (KQX62_17985)	3883958..3885898	+	1941	WP_264074144.1	phosphomethylpyrimidine synthase ThiC	-
KQX62_RS18080 (KQX62_17990)	3886249..3886539	+	291	WP_264074145.1	hypothetical protein	-
KQX62_RS18085 (KQX62_17995)	3886520..3887995	+	1476	WP_264074146.1	hypothetical protein	-
KQX62_RS18090 (KQX62_18000)	3888128..3888517	-	390	WP_264074147.1	ester cyclase	-
KQX62_RS18095 (KQX62_18005)	3888823..3889356	-	534	WP_264074148.1	GNAT family N-acetyltransferase	Toxin
KQX62_RS18100 (KQX62_18010)	3889344..3889682	-	339	WP_264076666.1	DUF1778 domain-containing protein	Antitoxin
KQX62_RS18105 (KQX62_18015)	3889782..3890294	-	513	WP_264074149.1	hypothetical protein	-
KQX62_RS18110 (KQX62_18020)	3890598..3891017	-	420	WP_264074150.1	hypothetical protein	-
KQX62_RS18115 (KQX62_18025)	3891064..3891618	-	555	WP_264074151.1	hypothetical protein	-
KQX62_RS18120 (KQX62_18030)	3891742..3892026	+	285	WP_264074152.1	hypothetical protein	-
KQX62_RS18125 (KQX62_18035)	3892195..3892383	+	189	WP_264074154.1	hypothetical protein	-
KQX62_RS18130 (KQX62_18040)	3892401..3893693	-	1293	WP_264074155.1	flavin-dependent oxidoreductase	-
KQX62_RS18135 (KQX62_18045)	3893979..3894533	+	555	WP_264074157.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (50-151)

Antitoxin

• Vibrio phage ICP1, Orf50 (31-107)

Sequences

Toxin

Protein

• Length: 178 a.a.
• Molecular weight: 19123.80 Da
• Isoelectric Point: 6.7007

>T206190 WP_264074148.1 NZ_CP076676:c3889356-3888823 [Rhodopseudomonas palustris]
MADIDDAPNQPRSRLSAPVPLTMQHDLSAFDCGEPVLNDWLRQRALKNESRFSRTYVVCEGNKVVGYFCVSAGAVERAAA
PGKVRRNAPDTIPVSVIGRLAVSRSHAGSGLGADLLSDALRRIALASQSIGIGAVLVHAKDDAAKRFYLRCAEFIEYPED
SWTLFLPIEAVVAALSE

Nucleotide

• Length: 534 bp

>T206190 NZ_CP102186:c4774267-4773734 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin

Protein

• Length: 113 a.a.
• Molecular weight: 12217.07 Da
• Isoelectric Point: 11.4488

>AT206190 WP_264076666.1 NZ_CP076676:c3889682-3889344 [Rhodopseudomonas palustris]
MAKTRVAPAKSARRSAAAAARGATSDAKGSINLRIETGTRQLIDDAAAVLGKTRTEFMVESARRQAVDVLLDQRLFTLDP
ERYDAFMQALDNPPAPGPKLKALLRRVPAWRT

Nucleotide

• Length: 339 bp

>AT206190 NZ_CP102186:c4774544-4774278 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA