Detailed information of TA system TA206189

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 2425405..2426896
• Replicon: chromosome
• Accession: NZ_CP076676
• Organism: Rhodopseudomonas palustris strain TLS06

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: KQX62_RS11255
• Protein ID: WP_264076461.1
• Coordinates: 2426018..2426896 (+)
• Length: 293 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: KQX62_RS11250
• Protein ID: WP_264076460.1
• Coordinates: 2425405..2426025 (+)
• Length: 207 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KQX62_RS11235 (KQX62_11195)	2420916..2422538	+	1623	WP_264076457.1	glutamine-hydrolyzing GMP synthase	-
KQX62_RS11240 (KQX62_11200)	2422619..2424046	-	1428	WP_264076458.1	hypothetical protein	-
KQX62_RS11245 (KQX62_11205)	2424172..2425080	+	909	WP_264076459.1	hypothetical protein	-
KQX62_RS11250 (KQX62_11210)	2425405..2426025	+	621	WP_264076460.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
KQX62_RS11255 (KQX62_11215)	2426018..2426896	+	879	WP_264076461.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
KQX62_RS11260 (KQX62_11220)	2427073..2428269	-	1197	WP_264076462.1	sodium/glutamate symporter	-
KQX62_RS11265	2428373..2428744	-	372	WP_264076463.1	helix-turn-helix domain-containing protein	-
KQX62_RS11270	2428765..2429223	-	459	WP_264076464.1	AraC family ligand binding domain-containing protein	-
KQX62_RS11275 (KQX62_11230)	2429375..2429770	+	396	WP_264076465.1	hypothetical protein	-
KQX62_RS11280 (KQX62_11235)	2429802..2430206	+	405	WP_264076466.1	hypothetical protein	-
KQX62_RS11285 (KQX62_11240)	2430324..2431304	-	981	WP_264076467.1	YafY family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2415453..2427045	11592

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (38-265)

Antitoxin

• Transcriptional regulator AbiEi antitoxin, N-terminal domain (10-92)

Sequences

Toxin

Protein

• Length: 293 a.a.
• Molecular weight: 32389.17 Da
• Isoelectric Point: 4.6748

>T206189 WP_264076461.1 NZ_CP076676:2426018-2426896 [Rhodopseudomonas palustris]
MAKAPTNVAKSVKDRLLNIARKEGRAFDVLLVRFALERLLYRLSISAHSDRFVLKGGMLVTVWVADDNRVTRDADFLGHG
DADPDRLIADFGEIMAIESDDGLAFDIDALAAMVIREEMEYGGVRLKTAAYLERTRIPVTIDIGFGDAMADATQRLDYPT
LLDLPAPQVRCYPPATVIAKKFQAMVELGVLNGRMKDYYDLWAIPRAIDISADDLDAAIIATFERRRTPIPKERPPGLSA
EMFGDEGKQRQWRAYAASLELDAISLESIIEAVWELVGPSCARIVARSDSEA

Nucleotide

• Length: 879 bp

>T206189 NZ_CP102186:4161435-4161653 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin

Protein

• Length: 207 a.a.
• Molecular weight: 22750.33 Da
• Isoelectric Point: 10.5816

>AT206189 WP_264076460.1 NZ_CP076676:2425405-2426025 [Rhodopseudomonas palustris]
MRARHDSQKAQLISLLETRSMMRAQDLREAGISAQTIARAVEAGEIDRISRGVYQKRGVEVEENQILAEALMRASKGVIA
MVSALAFHGLTDQMPRRVWMAIGTSDWAPVQSYPPLRIVRFTQPYLRQGIEHHVISGLDVPIYSIPKTLADLFRNPKLVD
RSVAVEGLRAALQQRKATPSAIAHAAKAGGAWKVMQPYLEALTSNG

Nucleotide

• Length: 621 bp

>AT206189 NZ_CP102186:4161034-4161408 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG