Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2126262..2126533 Replicon chromosome
Accession NZ_CP076654
Organism Escherichia coli strain NC19

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2126392..2126495 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2126262..2126533 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPE96_RS10210 2122817..2123479 - 663 WP_000944256.1 exodeoxyribonuclease X -
KPE96_RS10215 2123503..2124159 - 657 WP_216696500.1 carbon-nitrogen hydrolase family protein YobB -
KPE96_RS10220 2124261..2124491 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KPE96_RS10225 2124630..2125004 + 375 WP_000204699.1 CopC domain-containing protein YobA -
KPE96_RS10230 2125008..2125880 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
KPE96_RS10235 2125893..2126234 + 342 WP_000976492.1 YebY family protein -
- 2126262..2126533 - 272 - - Antitoxin
- 2126392..2126495 + 104 - - Toxin
KPE96_RS10240 2126630..2127286 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
KPE96_RS10245 2127287..2127478 - 192 WP_001296140.1 YebW family protein -
KPE96_RS10250 2127583..2127819 - 237 WP_001295499.1 YebV family protein -
KPE96_RS10255 2127937..2129376 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T206146 NZ_CP076654:2126392-2126495 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT206146 NZ_CP076654:c2126533-2126262 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References