Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1964424..1964894 Replicon chromosome
Accession NZ_CP076651
Organism Serratia ureilytica strain S24

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KQJ82_RS09125 Protein ID WP_240324795.1
Coordinates 1964670..1964894 (+) Length 75 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KQJ82_RS09120 Protein ID WP_230328427.1
Coordinates 1964424..1964624 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KQJ82_RS09090 (KQJ82_09090) 1959617..1960885 + 1269 WP_038874127.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
KQJ82_RS09095 (KQJ82_09095) 1960882..1962081 + 1200 WP_033652425.1 anaerobic glycerol-3-phosphate dehydrogenase subunit GlpC -
KQJ82_RS09100 (KQJ82_09100) 1962116..1962679 - 564 WP_025304887.1 DcrB family lipoprotein -
KQJ82_RS09105 (KQJ82_09105) 1962760..1963194 - 435 WP_033652424.1 GNAT family N-acetyltransferase -
KQJ82_RS09110 (KQJ82_09110) 1963236..1963895 - 660 WP_042783454.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
KQJ82_RS09115 (KQJ82_09115) 1964117..1964362 + 246 WP_025304890.1 sulfurtransferase TusA -
KQJ82_RS09120 (KQJ82_09120) 1964424..1964624 + 201 WP_230328427.1 stability determinant Antitoxin
KQJ82_RS09125 (KQJ82_09125) 1964670..1964894 + 225 WP_240324795.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KQJ82_RS09130 (KQJ82_09130) 1964954..1967272 - 2319 WP_196018786.1 zinc/cadmium/mercury/lead-transporting ATPase -
KQJ82_RS09135 (KQJ82_09135) 1967953..1969416 + 1464 WP_033644999.1 serralysin family metalloprotease -
KQJ82_RS09140 (KQJ82_09140) 1969471..1969848 + 378 WP_025304893.1 AprI/Inh family metalloprotease inhibitor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-73)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 75 a.a.        Molecular weight: 8670.25 Da        Isoelectric Point: 11.6785

>T206121 WP_240324795.1 NZ_CP076651:1964670-1964894 [Serratia ureilytica]
VGFIANDNPLAARKMKVLIMEAVTPAARHPRIFRRGRVDGTHEIPLHPHYLLIYQVLETHIRVLRVLHTRRQYP

Download         Length: 225 bp

>T206121 NZ_CP102143:c2056648-2056391 [Streptococcus suis]
ATGGGAATCCATTTTACAGACGACGCCTGGGAAGACTATCTTTATTGGCAGGGTCAGGATAAGAAAACACTGAAGAGAAT
CAATAAGATTATCAAGGATATGCAGCGACATCCTTTTGAAGGCATTGCCAAACCAGAACCTTTGAAGTATGATTATCAAG
GTGCCTGGTCTCGGAGAATTGATGCGGAGAATCGGTTGATTTATATGGTGGAAGCTGATCGGTTGTGCATCCTGTCGCTA
AAGGATCATTATAGGTGA

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7553.66 Da        Isoelectric Point: 4.2686

>AT206121 WP_230328427.1 NZ_CP076651:1964424-1964624 [Serratia ureilytica]
MMSILLLPTVAKMENEEHKQGYERWFLERVQEAMDEPWPGIPHDDVMAEMDAVIAAAEARINAKQA

Download         Length: 201 bp

>AT206121 NZ_CP102143:c2056910-2056650 [Streptococcus suis]
ATGGAAGCTATTGTATATTCCCATTTTCGAAATCACTTAAAGGACTATATGAAAAAGGTCAATGACGAGTTTGAACCTTT
GGTCGTGGTTAATAAAAATCCAGAGGAAGATATTGTTGTACTCTCAAAGAGTGAGTGGGATAGTTTACAAGAAACCCTCG
CTGTTGCTCGGAACACTTATCTGTCTCAAAAAGTCCTACGTGGTATGGCTAAAGTCAAAACGGGACAAACCCAAGAACGA
AACCTGATAGAGGCGGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References