Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2094456..2094727 Replicon chromosome
Accession NZ_CP076646
Organism Escherichia coli strain GD33

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2094586..2094689 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2094456..2094727 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP013_RS10000 2091011..2091673 - 663 WP_000944258.1 exodeoxyribonuclease X -
KP013_RS10005 2091697..2092353 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
KP013_RS10010 2092455..2092685 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KP013_RS10015 2092824..2093198 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KP013_RS10020 2093202..2094074 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
KP013_RS10025 2094087..2094428 + 342 WP_000976472.1 YebY family protein -
- 2094456..2094727 - 272 - - Antitoxin
- 2094586..2094689 + 104 - - Toxin
KP013_RS10030 2094824..2095480 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
KP013_RS10035 2095481..2095672 - 192 WP_001338167.1 YebW family protein -
KP013_RS10040 2095777..2096013 - 237 WP_001338166.1 YebV family protein -
KP013_RS10045 2096131..2097570 - 1440 WP_077252964.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T206094 NZ_CP076646:2094586-2094689 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT206094 NZ_CP076646:c2094727-2094456 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References