Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1173945..1174492 Replicon chromosome
Accession NZ_CP076643
Organism Vibrio ostreae strain OG9-811

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KNV97_RS11420 Protein ID WP_136486642.1
Coordinates 1173945..1174247 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KNV97_RS11425 Protein ID WP_136486645.1
Coordinates 1174235..1174492 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KNV97_RS11385 (KNV97_11385) 1169234..1169554 + 321 WP_218563142.1 DUF1840 domain-containing protein -
KNV97_RS11390 (KNV97_11390) 1169719..1170240 + 522 WP_218563143.1 DUF2058 domain-containing protein -
KNV97_RS11395 (KNV97_11395) 1170357..1170794 + 438 WP_136486636.1 DUF3859 domain-containing protein -
KNV97_RS11400 (KNV97_11400) 1171189..1171521 + 333 WP_218563144.1 SEC-C metal-binding domain-containing protein -
KNV97_RS11405 (KNV97_11405) 1171745..1172158 - 414 WP_218563422.1 GFA family protein -
KNV97_RS11410 (KNV97_11410) 1172297..1172815 - 519 WP_218563145.1 GNAT family N-acetyltransferase -
KNV97_RS21975 1172859..1172963 - 105 Protein_1029 DUF3265 domain-containing protein -
KNV97_RS11415 (KNV97_11415) 1172964..1173701 - 738 WP_218563146.1 SDR family oxidoreductase -
KNV97_RS11420 (KNV97_11420) 1173945..1174247 - 303 WP_136486642.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KNV97_RS11425 (KNV97_11425) 1174235..1174492 - 258 WP_136486645.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KNV97_RS11430 (KNV97_11430) 1175043..1175606 - 564 WP_218563147.1 pyridoxamine 5'-phosphate oxidase family protein -
KNV97_RS11435 (KNV97_11435) 1175826..1176038 - 213 WP_218563148.1 hypothetical protein -
KNV97_RS11440 (KNV97_11440) 1176063..1176176 - 114 WP_218563423.1 DUF3265 domain-containing protein -
KNV97_RS11445 (KNV97_11445) 1176177..1177019 - 843 WP_218563149.1 DUF5677 domain-containing protein -
KNV97_RS11450 (KNV97_11450) 1177135..1178685 - 1551 WP_218563467.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11710.70 Da        Isoelectric Point: 5.1972

>T206062 WP_136486642.1 NZ_CP076643:c1174247-1173945 [Vibrio ostreae]
MAKIIWTEPVLSDLDDIAEYIALENFVAAKQLVQTIFAKVERLETLPESGRIPPELEHLSYREVVVNPCRVFYKQDGDKV
FILFVMRVERDLRKFLLSKQ

Download         Length: 303 bp

>T206062 NZ_CP102089:1013708-1013887 [Staphylococcus capitis subsp. capitis]
ATGAATAAAGAATATGAATCTAAATTGAATTATCATGAAGAAGAAAATGCTATGGTTACAGATTTAGATGATTTAAAAGA
ATTAGGAAAAGAAATGGAACAAATTTCAGAAGAAAATGATGAAGATAAATTAAACCAATCTCATGATGAAGATGTTCATT
CTGACCTTAATAATGAATAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9698.21 Da        Isoelectric Point: 6.7273

>AT206062 WP_136486645.1 NZ_CP076643:c1174492-1174235 [Vibrio ostreae]
MKVELVTSLKRQATKILADLHDTKEPVLITEHGKPSAYLVDVDDYEFMQNRLSILEGIARGERALTDGKMVSHEEAKDKM
SKWLK

Download         Length: 258 bp

>AT206062 NZ_CP102089:1013081-1013680 [Staphylococcus capitis subsp. capitis]
ATGGCAATGAACTTTAAAGTATTTGAAAATAGTGAAAGAGTAGCAGAATATGCTGCAGATATTATTCGTAAACAATTTAA
TAATAATCCAACTACAATTGCAGGTTTTCACTTAGAAAAAGATCACGCACCTGTATTAGATGAACTTAAGAAAAATGTAG
ATACGCATGCTGTAGATTTCAGCCAAATCAATATTTTAGATTATGATGATAATAGATCTTATTATGAAGCATTAGGTGTA
CCTGAAAGCCAAGTGTATTCAATTTCTTACGAACAAGATGCAATTGATTTTATTTCAGATAAAATGAAAACTAAAGAAAA
TAAAGGTAAATTAATCCTTCAAGTTCTTTCAATTGATGAAAGTGGCAAGTTAGATGTAAGTGTACGTCAAGGCCTTATGG
AAGCTAGAGAAATTTTCTTAGTTGTTACAGGTAGTAATAAACGTGAAGTTATTGAAAAACTTTATCGTGAAAACGGCAAA
TCTAGTTATGAGCCAGCAGATCTTAAAGCACACCGCATGGTAAATGTTATTTTAGATAAAGAAGCGGCTGCAGGATTACC
TGAGGATGTTAAAGAATACTTCACAGCACGTTATGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References