206059

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2112258..2112627 Replicon chromosome
Accession NZ_CP076628
Organism Xanthomonas arboricola pv. pruni strain IVIA 2626.1

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag KP026_RS09290 Protein ID WP_016904515.1
Coordinates 2112258..2112392 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag KP026_RS09295 Protein ID WP_006451340.1
Coordinates 2112475..2112627 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP026_RS09275 (KP026_09260) 2109325..2110269 - 945 WP_039512622.1 MBL fold metallo-hydrolase -
KP026_RS09280 (KP026_09265) 2110327..2111616 - 1290 WP_039814994.1 tryptophan--tRNA ligase -
KP026_RS09285 (KP026_09270) 2111798..2112007 - 210 WP_039512625.1 CsbD family protein -
KP026_RS09290 (KP026_09275) 2112258..2112392 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
KP026_RS09295 (KP026_09280) 2112475..2112627 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
KP026_RS09300 (KP026_09285) 2112737..2113660 - 924 WP_039512664.1 arginase -
KP026_RS09305 (KP026_09290) 2114136..2114588 + 453 WP_039512628.1 roadblock/LC7 domain-containing protein -
KP026_RS09310 (KP026_09295) 2114652..2115011 + 360 WP_039512630.1 hypothetical protein -
KP026_RS09315 (KP026_09300) 2115105..2116022 + 918 WP_039512632.1 hypothetical protein -
KP026_RS09320 (KP026_09305) 2116019..2116561 + 543 WP_016904520.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T206059 WP_016904515.1 NZ_CP076628:c2112392-2112258 [Xanthomonas arboricola pv. pruni]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T206059 NZ_CP102089:c295548-295279 [Staphylococcus capitis subsp. capitis]
ATGAGTAAGTTTAGTGTAGCTTTTACAGCTCAAGCATTTAAAGATTATCAATATTGGCAACAACACAATCAAAATTATTT
TAAAAAAGTGAATTCTTTACTTAAAAGTATTGCAAGAGATGGTTGTGTTGATGGTATTGGAAAACCAGAAGCATTAAAAG
GAAACTACGAAGGCTATTTCAGTAGAAGAGTTTCAATAGAACAACGATTAATATACAAAATTAAGGATGATTCAATATTC
GTAGTGTCTTGCAGATTTCATTATCAATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT206059 WP_006451340.1 NZ_CP076628:c2112627-2112475 [Xanthomonas arboricola pv. pruni]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT206059 NZ_CP102089:c295798-295541 [Staphylococcus capitis subsp. capitis]
ATGCCTTCAGTTAATTATTCAAACGCTAGACAGAATTTCAAAGAACTTATTACTAAAGTGAACGAGGATAGTGTGGCTTA
CACTATTACGACAAAGGAAAATGAAAATGCAGTGATTTTAGCTGAAAAGGATTATAATGCGATGTTGGAAACGATGTACC
TTCTATCCAATCTCGCTAATGTGTCTCACTTAAATCAATCAATTATGGAATTGAATCATAACCAAACAATTACAATAGAG
ATTGATGATAATGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References