Detailed information of TA system TA206055

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): Hha-TomB/-
• Location: 895428..896053
• Replicon: chromosome
• Accession: NZ_CP076623
• Organism: Morganella morganii strain CTX51T

Toxin (Protein)

• Gene name: Hha
• Uniprot ID: A0A0A2RCL2
• Locus tag: KQH80_RS04105
• Protein ID: WP_024474604.1
• Coordinates: 895428..895631 (-)
• Length: 68 a.a.

Antitoxin (Protein)

• Gene name: TomB
• Uniprot ID: -
• Locus tag: KQH80_RS04110
• Protein ID: WP_230060479.1
• Coordinates: 895694..896053 (-)
• Length: 120 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KQH80_RS04085 (KQH80_04080)	891967..892305	+	339	WP_046893175.1	P-II family nitrogen regulator	-
KQH80_RS04090 (KQH80_04085)	892325..893614	+	1290	WP_230061319.1	ammonium transporter AmtB	-
KQH80_RS04095 (KQH80_04090)	893675..894538	-	864	WP_054424719.1	acyl-CoA thioesterase II	-
KQH80_RS04105 (KQH80_04100)	895428..895631	-	204	WP_024474604.1	HHA domain-containing protein	Toxin
KQH80_RS04110 (KQH80_04105)	895694..896053	-	360	WP_230060479.1	Hha toxicity modulator TomB	Antitoxin
KQH80_RS04115 (KQH80_04110)	896615..899791	-	3177	WP_046893179.1	efflux RND transporter permease subunit	-
KQH80_RS04120 (KQH80_04115)	899806..900999	-	1194	WP_046893180.1	efflux RND transporter periplasmic adaptor subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Haemolysin expression modulating, HHA (8-64)

Antitoxin

• Biofilm formation regulator YbaJ (1-113)

Sequences

Toxin

Protein

• Length: 68 a.a.
• Molecular weight: 8073.39 Da
• Isoelectric Point: 6.9770

>T206055 WP_024474604.1 NZ_CP076623:c895631-895428 [Morganella morganii]
MTKLDYLMRLRKCTSIETLERVIEKNKYELTDDELEVFYSAADHRLAELTMNKLYDKIPASVWKFVR

Nucleotide

• Length: 204 bp

>T206055 NZ_CP102087:c1490228-1490049 [Staphylococcus capitis subsp. capitis]
ATGAATAAAGAATATGAATCTAAATTGAATTATCATGAAGAAGAAAATGCTATGGTTACAGATTTAGATGATTTAAAAGA
ATTAGGAAAAGAAATGGAACAAATTTCAGAAGAAAATGATGAAGATAAATTAAACCAATCTCATGATGAAGATGTTCATT
CTGACCTTAATAATGAATAA

Antitoxin

Protein

• Length: 120 a.a.
• Molecular weight: 13874.58 Da
• Isoelectric Point: 4.2870

>AT206055 WP_230060479.1 NZ_CP076623:c896053-895694 [Morganella morganii]
MDEYSPRNYDIAVLKYLCDELCREGTQTLFRSNNFWVNDLASDSNLKLNELLGYIADVTWSFKIKHTQNKDLISFVDEYI
DETYALFGQMEVSFNDVEEWKKMASLVSSMLTSEGHLVH

Nucleotide

• Length: 360 bp

>AT206055 NZ_CP102087:c1490855-1490256 [Staphylococcus capitis subsp. capitis]
ATGGCAATGAACTTTAAAGTATTTGAAAATAGTGAAAGAGTAGCAGAATATGCTGCAGATATTATTCGTAAACAATTTAA
TAATAATCCAACTACAATTGCAGGTTTTCACTTAGAAAAAGATCACGCACCTGTATTAGATGAACTTAAGAAAAATGTAG
ATACGCATGCTGTAGATTTCAGCCAAATCAATATTTTAGATTATGATGATAATAGATCTTATTATGAAGCATTAGGTGTA
CCTGAAAGCCAAGTGTATTCAATTTCTTACGAACAAGATGCAATTGATTTTATTTCAGATAAAATGAAAACTAAAGAAAA
TAAAGGTAAATTAATCCTTCAAGTTCTTTCAATTGATGAAAGTGGCAAGTTAGATGTAAGTGTACGTCAAGGCCTTATGG
AAGCTAGAGAAATTTTCTTAGTTGTTACAGGTAGTAATAAACGTGAAGTTATTGAAAAACTTTATCGTGAAAACGGCAAA
TCTAGTTATGAGCCAGCAGATCTTAAAGCACACCGCATGGTAAATGTTATTTTAGATAAAGAAGCGGCTGCAGGATTACC
TGAGGATGTTAAAGAATACTTCACAGCACGTTATGTTTAA

Structures

Toxin

• AlphaFold DB: A0A0A2RCL2