Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4743170..4743539 Replicon chromosome
Accession NZ_CP076619
Organism Xanthomonas arboricola pv. corylina strain CFBP 1846

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag KP021_RS20500 Protein ID WP_016904515.1
Coordinates 4743170..4743304 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag KP021_RS20505 Protein ID WP_006451340.1
Coordinates 4743387..4743539 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KP021_RS20485 (KP021_20425) 4740237..4741181 - 945 WP_039512622.1 MBL fold metallo-hydrolase -
KP021_RS20490 (KP021_20430) 4741239..4742528 - 1290 WP_039814994.1 tryptophan--tRNA ligase -
KP021_RS20495 (KP021_20435) 4742710..4742919 - 210 WP_039512625.1 CsbD family protein -
KP021_RS20500 (KP021_20440) 4743170..4743304 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
KP021_RS20505 (KP021_20445) 4743387..4743539 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
KP021_RS20510 (KP021_20450) 4743649..4744572 - 924 WP_039512664.1 arginase -
KP021_RS20515 (KP021_20455) 4745051..4745503 + 453 WP_016904517.1 roadblock/LC7 domain-containing protein -
KP021_RS20520 (KP021_20460) 4745567..4745926 + 360 WP_016904518.1 hypothetical protein -
KP021_RS20525 (KP021_20465) 4745991..4746908 + 918 WP_249452600.1 hypothetical protein -
KP021_RS20530 (KP021_20470) 4746905..4747447 + 543 WP_016904520.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T206053 WP_016904515.1 NZ_CP076619:c4743304-4743170 [Xanthomonas arboricola pv. corylina]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T206053 NZ_CP102087:c496668-496483 [Staphylococcus capitis subsp. capitis]
GTGAGTTTGCATTTTCAAATATTGTTATGGCTAGCAATTATATTTATTGTCGCTGGAGCTATTATTTTAACAATTATGCT
TAAGACTAAGAAAGAAGAAAGAAAAGAATCTTATTTAGGATTTACTGTAATATTCTTGATTTTTGGATTTGCTATGCTTA
TATACACACTCATTTTCGGGTTGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT206053 WP_006451340.1 NZ_CP076619:c4743539-4743387 [Xanthomonas arboricola pv. corylina]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT206053 NZ_CP102087:c496958-496701 [Staphylococcus capitis subsp. capitis]
ATGAAAATATTTAGTATAAATGTGATTAATATTTTATTGACCATATTATTTATAGCCTTTAATGTGCTTATAACTTATAA
CGCAAATGTTGATAATCAATTATGGTTGATACCAGGATTATGTATTTGTGGCGTCGCTTTATTCACTAGTCTAATAATAG
CTATTATTTACACTGATTTGCTAAGCGAAATTATATTTTTCATAAATATTGTATTAGCACTTTACTATATTTATCCTATT
TTTTACGACTTCTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References