Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 2863664..2864330 | Replicon | chromosome |
Accession | NZ_CP076594 | ||
Organism | Erwinia amylovora isolate CP20086202 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | A0A830ZTB8 |
Locus tag | KQH36_RS13035 | Protein ID | WP_004161808.1 |
Coordinates | 2863664..2864083 (-) | Length | 140 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | D4HWC2 |
Locus tag | KQH36_RS13040 | Protein ID | WP_004155593.1 |
Coordinates | 2864064..2864330 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KQH36_RS13020 (KQH36_13020) | 2859656..2861335 | + | 1680 | WP_004155599.1 | type III effector | - |
KQH36_RS13025 (KQH36_13025) | 2861845..2862798 | + | 954 | WP_004155597.1 | DMT family transporter | - |
KQH36_RS13030 (KQH36_13030) | 2863028..2863546 | + | 519 | WP_004155596.1 | flavodoxin FldB | - |
KQH36_RS13035 (KQH36_13035) | 2863664..2864083 | - | 420 | WP_004161808.1 | protein YgfX | Toxin |
KQH36_RS13040 (KQH36_13040) | 2864064..2864330 | - | 267 | WP_004155593.1 | FAD assembly factor SdhE | Antitoxin |
KQH36_RS13045 (KQH36_13045) | 2864556..2865542 | + | 987 | WP_004155590.1 | tRNA-modifying protein YgfZ | - |
KQH36_RS13050 (KQH36_13050) | 2865543..2866202 | - | 660 | WP_004155588.1 | hemolysin III family protein | - |
KQH36_RS13055 (KQH36_13055) | 2866415..2867023 | + | 609 | WP_004155587.1 | HD domain-containing protein | - |
KQH36_RS13060 (KQH36_13060) | 2867128..2867857 | - | 730 | Protein_2518 | SDR family oxidoreductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 16366.46 Da Isoelectric Point: 11.9444
>T206009 WP_004161808.1 NZ_CP076594:c2864083-2863664 [Erwinia amylovora]
VVLWQCELRPSRLAQRFSLLLHGAVMLALLLPTWPASSGLVRMLLLVLVLLECIRSRRRIGRRQGDIALLEGHELRWRQR
EWCIISRPWLTGQAILLLLQDTHGQRERLWLFADGMEKRNWRQLRLQLLNSKVQGNGWC
VVLWQCELRPSRLAQRFSLLLHGAVMLALLLPTWPASSGLVRMLLLVLVLLECIRSRRRIGRRQGDIALLEGHELRWRQR
EWCIISRPWLTGQAILLLLQDTHGQRERLWLFADGMEKRNWRQLRLQLLNSKVQGNGWC
Download Length: 420 bp
>T206009 NZ_CP102065:467437-467553 [Enterococcus faecalis]
ATGTTTTTGTCCGTTGAAGCAGCGTTGGGACTGATGATTGGTTTTGCAACACTTGTTGTGACCATTATCTTCGGTATCTT
AGCGCTTGTCTTAGACAACAAAAATAACCGTTCATAA
ATGTTTTTGTCCGTTGAAGCAGCGTTGGGACTGATGATTGGTTTTGCAACACTTGTTGTGACCATTATCTTCGGTATCTT
AGCGCTTGTCTTAGACAACAAAAATAACCGTTCATAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 10498.07 Da Isoelectric Point: 6.4605
>AT206009 WP_004155593.1 NZ_CP076594:c2864330-2864064 [Erwinia amylovora]
MDITNKSRIHWACRRGMRELDISIMPFFQYEFDSLNDSDKRLFVRLLESDDPDLFNWLMNHGEPADVELKRMVALIQQRN
KQRGPVAM
MDITNKSRIHWACRRGMRELDISIMPFFQYEFDSLNDSDKRLFVRLLESDDPDLFNWLMNHGEPADVELKRMVALIQQRN
KQRGPVAM
Download Length: 267 bp
>AT206009 NZ_CP102065:c467669-467464 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A830ZTB8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A831A3F0 |