Detailed information of TA system TA205947

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-DinJ
• Location: 241429..242000
• Replicon: chromosome
• Accession: NZ_CP076545
• Organism: Collinsella sp. zg1085

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KPC83_RS01015
• Protein ID: WP_216278745.1
• Coordinates: 241722..242000 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: KPC83_RS01010
• Protein ID: WP_216278744.1
• Coordinates: 241429..241719 (+)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KPC83_RS00980 (KPC83_00980)	236957..237238	+	282	WP_216278739.1	PTS sugar transporter subunit IIB	-
KPC83_RS00990 (KPC83_00990)	237559..238809	+	1251	WP_216278740.1	serine hydroxymethyltransferase	-
KPC83_RS00995 (KPC83_00995)	238962..239135	-	174	WP_216278741.1	hypothetical protein	-
KPC83_RS01000 (KPC83_01000)	239226..240518	+	1293	WP_216278742.1	serine--tRNA ligase	-
KPC83_RS01005 (KPC83_01005)	240771..241109	+	339	WP_216278743.1	hypothetical protein	-
KPC83_RS01010 (KPC83_01010)	241429..241719	+	291	WP_216278744.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
KPC83_RS01015 (KPC83_01015)	241722..242000	+	279	WP_216278745.1	type II toxin-antitoxin system YafQ family toxin	Toxin
KPC83_RS01020 (KPC83_01020)	242198..245146	-	2949	WP_216278746.1	hypothetical protein	-
KPC83_RS01025 (KPC83_01025)	245301..246251	+	951	WP_216278747.1	FAD:protein FMN transferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (3-91)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-69)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10658.30 Da
• Isoelectric Point: 7.2749

>T205947 WP_216278745.1 NZ_CP076545:241722-242000 [Collinsella sp. zg1085]
MLELRATSKFRKDYKRIEKRGYNLALLEAVLEKLLNQEPLEARYKDHALTGSYAGFRECHIQPDWLFIYAVEKDQLILVA
AGTGTHADLFNM

Nucleotide

• Length: 279 bp

>T205947 NZ_CP101937:2048983-2049075 [Bacillus subtilis]
ATGTCAACATTCCAGGCATTAATGCTAATGCTTGCAATCGGGTCGTTTATAATCGCCCTATTGACGTATATAGAAAAAAT
AGACCTCCCTTGA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 10729.09 Da
• Isoelectric Point: 4.4002

>AT205947 WP_216278744.1 NZ_CP076545:241429-241719 [Collinsella sp. zg1085]
MAKTANINLRIEPQVKRDAEAIFESFGISVTDAINIFLHQSIMEQGFPFAIQRPRYNAETEAALQEARDILSGKIPAKSY
GSARELFADLDLEAEE

Nucleotide

• Length: 291 bp

>AT205947 NZ_CP101937:c2049229-2049056 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT