205941

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 840619..840988 Replicon chromosome
Accession NZ_CP076534
Organism Xanthomonas arboricola pv. corylina strain IVIA 3978

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0B2CMD0
Locus tag KPG65_RS03525 Protein ID WP_016904515.1
Coordinates 840619..840753 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag KPG65_RS03530 Protein ID WP_006451340.1
Coordinates 840836..840988 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KPG65_RS03510 (KPG65_03525) 837686..838630 - 945 WP_039512622.1 MBL fold metallo-hydrolase -
KPG65_RS03515 (KPG65_03530) 838688..839977 - 1290 WP_039814994.1 tryptophan--tRNA ligase -
KPG65_RS03520 (KPG65_03535) 840159..840368 - 210 WP_039512625.1 CsbD family protein -
KPG65_RS03525 (KPG65_03540) 840619..840753 - 135 WP_016904515.1 entericidin A/B family lipoprotein Toxin
KPG65_RS03530 (KPG65_03545) 840836..840988 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
KPG65_RS03535 (KPG65_03550) 841098..842021 - 924 WP_039512664.1 arginase -
KPG65_RS03540 (KPG65_03555) 842497..842949 + 453 WP_039512628.1 roadblock/LC7 domain-containing protein -
KPG65_RS03545 (KPG65_03560) 843013..843372 + 360 WP_016904518.1 hypothetical protein -
KPG65_RS03550 (KPG65_03565) 843467..844384 + 918 WP_039814989.1 hypothetical protein -
KPG65_RS03555 (KPG65_03570) 844381..844923 + 543 WP_016904520.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4443.26 Da        Isoelectric Point: 9.3487

>T205941 WP_016904515.1 NZ_CP076534:c840753-840619 [Xanthomonas arboricola pv. corylina]
MKRAIVLLVLSVLSVGMLSGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T205941 NZ_CP101933:509128-509478 [Bacillus subtilis subsp. natto]
TTGATTGTGAAACGCGGCGATGTTTATTTTGCTGATTTATCTCCTGTTGTTGGCTCAGAGCAAGGCGGGGTGCGCCCGGT
CTTAGTGATCCAAAATGACATCGGAAATCGCTTCAGCCCAACTGCTATTGTTGCAGCCATAACAGCACAAATACAGAAAG
CGAAATTACCAACCCACGTCGAAATCGATGCAAAACGCTACGGTTTTGAAAGAGATTCCGTTATTTTGCTGGAGCAAATT
CGGACGATTGACAAGCAAAGGTTAACGGATAAGATTACTCATCTGGATGATGAAATGATGGATAAGGTTGATGAAGCCTT
ACAAATCAGTTTGGCACTCATTGATTTTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT205941 WP_006451340.1 NZ_CP076534:c840988-840836 [Xanthomonas arboricola pv. corylina]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT205941 NZ_CP101933:508842-509123 [Bacillus subtilis subsp. natto]
TTGTCTGAATCCAGCGCAAGAACCGAAATGAAAATCAGCTTGCCCGAAAACCTAGTAGCTGAATTGGATGGTGTAGCGAT
GCGGGAGAAACGAAGCAGAAACGAACTGATATCACAAGCAGTGAGAGCATATGTCAGCGAACGAACAACTCGTCACAACC
GTGATTTGATGAGACGCGGCTATATGGAAATGGCGAAAATCAACCTGAATATTTCTTCTGAGGCTCACTTTGCGGAGTGC
GAGGCTGAAACGACAGTTGAGCGCTTAGTCAGCGGAGGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0B2CMD0

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References