Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2032724..2032869 | Replicon | chromosome |
| Accession | NZ_CP076518 | ||
| Organism | Klebsiella pneumoniae strain K186 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2032760..2032862 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2032724..2032869 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KNW01_RS09975 (KNW01_09975) | 2027854..2029914 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| KNW01_RS09980 (KNW01_09980) | 2029918..2030577 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| KNW01_RS09985 (KNW01_09985) | 2030656..2030886 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| KNW01_RS09990 (KNW01_09990) | 2030999..2031373 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| KNW01_RS09995 (KNW01_09995) | 2031377..2032246 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| KNW01_RS10000 (KNW01_10000) | 2032263..2032601 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2032724..2032869 | - | 146 | - | - | Antitoxin |
| - | 2032760..2032862 | + | 103 | - | - | Toxin |
| KNW01_RS10005 (KNW01_10005) | 2033238..2033381 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| KNW01_RS10010 (KNW01_10010) | 2033486..2034454 | - | 969 | WP_073971755.1 | VirK/YbjX family protein | - |
| KNW01_RS10015 (KNW01_10015) | 2034611..2035264 | + | 654 | WP_032441330.1 | protein-serine/threonine phosphatase | - |
| KNW01_RS10020 (KNW01_10020) | 2035261..2035452 | - | 192 | WP_002911395.1 | YebW family protein | - |
| KNW01_RS10025 (KNW01_10025) | 2035550..2035789 | - | 240 | WP_002911393.1 | YebV family protein | - |
| KNW01_RS10030 (KNW01_10030) | 2035905..2037338 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T205893 NZ_CP076518:2032760-2032862 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT205893 NZ_CP076518:c2032869-2032724 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
