Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | spoIISABC/SpoIISA-SpoIISB |
Location | 1231908..1232825 | Replicon | chromosome |
Accession | NZ_CP076514 | ||
Organism | Bacillus velezensis strain WB |
Toxin (Protein)
Gene name | spoIISA | Uniprot ID | - |
Locus tag | KNV92_RS06440 | Protein ID | WP_191073306.1 |
Coordinates | 1232079..1232825 (-) | Length | 249 a.a. |
Antitoxin (Protein)
Gene name | spoIISB | Uniprot ID | I2HQ14 |
Locus tag | KNV92_RS06435 | Protein ID | WP_003154807.1 |
Coordinates | 1231908..1232078 (-) | Length | 57 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KNV92_RS06400 (KNV92_06400) | 1227141..1228763 | + | 1623 | WP_094247021.1 | pyocin knob domain-containing protein | - |
KNV92_RS06405 (KNV92_06405) | 1228776..1229147 | + | 372 | WP_070081681.1 | XkdW family protein | - |
KNV92_RS06410 (KNV92_06410) | 1229152..1229349 | + | 198 | WP_071391956.1 | XkdX family protein | - |
KNV92_RS06415 (KNV92_06415) | 1229406..1230167 | + | 762 | WP_094247020.1 | phage portal protein | - |
KNV92_RS06420 (KNV92_06420) | 1230219..1230482 | + | 264 | WP_003154815.1 | hemolysin XhlA family protein | - |
KNV92_RS06425 (KNV92_06425) | 1230496..1230759 | + | 264 | WP_003154813.1 | phage holin | - |
KNV92_RS06430 (KNV92_06430) | 1230773..1231651 | + | 879 | WP_045207177.1 | N-acetylmuramoyl-L-alanine amidase | - |
KNV92_RS19265 | 1231686..1231811 | - | 126 | WP_003154809.1 | hypothetical protein | - |
KNV92_RS06435 (KNV92_06435) | 1231908..1232078 | - | 171 | WP_003154807.1 | type II toxin-antitoxin system SpoIISB family antitoxin | Antitoxin |
KNV92_RS06440 (KNV92_06440) | 1232079..1232825 | - | 747 | WP_191073306.1 | type II toxin-antitoxin system SpoIISA family toxin | Toxin |
KNV92_RS06445 (KNV92_06445) | 1232930..1233928 | - | 999 | WP_003154805.1 | inorganic phosphate transporter | - |
KNV92_RS06450 (KNV92_06450) | 1233941..1234558 | - | 618 | WP_003154804.1 | DUF47 domain-containing protein | - |
KNV92_RS06455 (KNV92_06455) | 1234844..1236160 | - | 1317 | WP_094247018.1 | amino acid permease | - |
KNV92_RS06460 (KNV92_06460) | 1236483..1237433 | + | 951 | WP_077722102.1 | ring-cleaving dioxygenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Prophage | - | - | 1198181..1289951 | 91770 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 249 a.a. Molecular weight: 29047.54 Da Isoelectric Point: 4.7755
>T205883 WP_191073306.1 NZ_CP076514:c1232825-1232079 [Bacillus velezensis]
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVVGAMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG
MLLFFQIMVWTMAAALILYVYASWRYEAKVKEKMFAIRKTWYLLFVVGAMVYWTYDPESLFAAWRQYLIVAVCFALIDAF
IFLSAYIKKLAGNELETDTREILEENNEMLHSYLEKLKTYQYLLKNEPIHVYYGSTEAYAEGISRLLAAYAEKMNVTASL
CDYSAQSDKDRLTEHMPDAADVQSRLNRKDVYYDQKGRLVLIPFTVQNRHYVIKLTSENLLTEFDYLLFTSLTSIYDLML
PIEEEGDG
Download Length: 747 bp
>T205883 NZ_CP101921:2716821-2716928 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 57 a.a. Molecular weight: 6676.74 Da Isoelectric Point: 10.9273
>AT205883 WP_003154807.1 NZ_CP076514:c1232078-1231908 [Bacillus velezensis]
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA
MEQAFQNGQPEQRAKPFKMFKKRSMTSIASYQVSPHTARIFKENERLIDKYKQKKA
Download Length: 171 bp
>AT205883 NZ_CP101921:c2716771-2716708 [Escherichia coli]
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTAAAACCTCTCAACGTGCGGGGGTTTTCT
TCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTAAAACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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