Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3820311..3820582 Replicon chromosome
Accession NZ_CP076470
Organism Escherichia coli strain DH5a

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3820441..3820544 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3820311..3820582 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KN807_RS18335 3816866..3817528 - 663 WP_000944256.1 exodeoxyribonuclease X -
KN807_RS18340 3817552..3818208 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
KN807_RS18345 3818310..3818540 - 231 WP_000916763.1 DNA polymerase III subunit theta -
KN807_RS18350 3818679..3819053 + 375 WP_000168747.1 CopC domain-containing protein YobA -
KN807_RS18355 3819057..3819929 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
KN807_RS18360 3819942..3820283 + 342 WP_000976476.1 YebY family protein -
- 3820311..3820582 - 272 - - Antitoxin
- 3820441..3820544 + 104 - - Toxin
KN807_RS18365 3820679..3821335 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
KN807_RS18370 3821336..3821527 - 192 WP_000457842.1 YebW family protein -
KN807_RS18375 3821632..3821868 - 237 WP_001295499.1 YebV family protein -
KN807_RS18380 3821986..3823425 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T205738 NZ_CP076470:3820441-3820544 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT205738 NZ_CP076470:c3820582-3820311 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References