Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DhiAT/dnstrm_HI1420(antitoxin)
Location 4044727..4045481 Replicon chromosome
Accession NZ_CP076386
Organism Dickeya dadantii strain S3-1

Toxin (Protein)


Gene name dhiT Uniprot ID -
Locus tag KNV89_RS17805 Protein ID WP_216282363.1
Coordinates 4044727..4044984 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name dhiA Uniprot ID -
Locus tag KNV89_RS17810 Protein ID WP_216282364.1
Coordinates 4044993..4045481 (+) Length 163 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KNV89_RS17795 (KNV89_17795) 4041488..4043638 - 2151 WP_216282361.1 formate dehydrogenase subunit alpha -
KNV89_RS17800 (KNV89_17800) 4043673..4044215 - 543 WP_216282362.1 4Fe-4S dicluster domain-containing protein -
KNV89_RS17805 (KNV89_17805) 4044727..4044984 + 258 WP_216282363.1 DUF4160 domain-containing protein Toxin
KNV89_RS17810 (KNV89_17810) 4044993..4045481 + 489 WP_216282364.1 DUF2442 domain-containing protein Antitoxin
KNV89_RS17815 (KNV89_17815) 4045560..4046054 - 495 WP_216282365.1 hydrogenase maturation peptidase HycI -
KNV89_RS17820 (KNV89_17820) 4046047..4046445 - 399 WP_216282366.1 formate hydrogenlyase maturation HycH family protein -
KNV89_RS17825 (KNV89_17825) 4046442..4047233 - 792 WP_216282367.1 NADH-quinone oxidoreductase subunit B family protein -
KNV89_RS17830 (KNV89_17830) 4047230..4047799 - 570 WP_216282368.1 hydrogenase 4 subunit H -
KNV89_RS17835 (KNV89_17835) 4047810..4049537 - 1728 WP_216282369.1 hydrogenase large subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Protein of unknown function DUF4160

(9-73)

Antitoxin

Protein of unknown function DUF2442

(4-71)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10003.61 Da        Isoelectric Point: 7.1842

>T205605 WP_216282363.1 NZ_CP076386:4044727-4044984 [Dickeya dadantii]
MPEIDRLAGLIFYLYFYDDDRHHLPHVHVCYGDDELIIAIDTGVEIEGYLPNSKRKMAIKHINTHRQHLLEMWKLAVKGR
HPGKL

Download         Length: 258 bp

>T205605 NZ_CP101770:746520-747005 [Klebsiella pneumoniae]
ATGATCTCGGCACCAGAACCGCTTCATGCCGGGCATATTCTTACCCCGTTTTGCTGCGGTATAGATTCCATGGATCACTG
GCTGAAACAGCGGGCGATGAAAAATCAGGTTACTGGCGCATCCCGCACCTTTGTCTGCTGCGACGACGCGAAGGTGATGG
CTTACTACTCACTGGCTTCCAGCGCTGTGACGACAAATACTGCGCCGGGTCGTTTTCGCCGCAATATGCCTGCCCCGATC
CCGGTTGTGGTACTGGGTCGTCTGGCGGTGGATAAATCACTACATGGGAAAGGTGTCGGGCGGGCCCTGGTACGTGATGC
CGGGCTGCGTGTGATTCAGGTGGCGGAGACTATCGGCATTCGCGGGATGCTGGTTCACGCCCTGTCGGATGAAGCACGGG
ATTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGAGGGATTTGGTTAAT
GCCTGA

Antitoxin


Download         Length: 163 a.a.        Molecular weight: 17967.54 Da        Isoelectric Point: 6.8729

>AT205605 WP_216282364.1 NZ_CP076386:4044993-4045481 [Dickeya dadantii]
MHKIIDVDVTGDFTLRLTYEDGLICDVDLYQYAPDPVFSNASLFIKFGLLPDGALEWQPDIKISASDLRKKGVYVGHTLA
VRERRFADVISRAFYDAVIENRPEILQAALKTAVEKHGNSTVAKEAGAKSRTSLYKSLNKNTNVSLATVVSLAHTVLQLE
EK

Download         Length: 489 bp

>AT205605 NZ_CP101770:746230-746523 [Klebsiella pneumoniae]
ATGCCAGCCGCAAACAGCATGTCCATAAAACGCGAAACGTTAAATCTGCGCATTAAACCTGCCGAACGCGATCTTATTGA
TCGGGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAGGCCGCCCGCGCTGCCGCTGAGGAAGCGCTGA
TTGAGCAACGCATCATTATGGCCGATCCGCAGGCTTATCAGGAATTTCTCGCTCGTCTGGATCAGGCTCCTGCACCTAAT
GCCGCACTGCGTAAAACTATGCAGACCCCTGCGCCGTGGGAACAGGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References