Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3059392..3060070 Replicon chromosome
Accession NZ_CP076386
Organism Dickeya dadantii strain S3-1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag KNV89_RS13640 Protein ID WP_216281604.1
Coordinates 3059639..3060070 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag KNV89_RS13635 Protein ID WP_013316361.1
Coordinates 3059392..3059658 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KNV89_RS13610 (KNV89_13610) 3055182..3055832 + 651 WP_216281583.1 LysE family translocator -
KNV89_RS13615 (KNV89_13615) 3055874..3056500 + 627 WP_216281596.1 hypothetical protein -
KNV89_RS13620 (KNV89_13620) 3056572..3057180 - 609 WP_216281599.1 HD domain-containing protein -
KNV89_RS13625 (KNV89_13625) 3057389..3058039 + 651 WP_216281601.1 hemolysin III family protein -
KNV89_RS13630 (KNV89_13630) 3058112..3059092 - 981 WP_216281602.1 tRNA-modifying protein YgfZ -
KNV89_RS13635 (KNV89_13635) 3059392..3059658 + 267 WP_013316361.1 FAD assembly factor SdhE Antitoxin
KNV89_RS13640 (KNV89_13640) 3059639..3060070 + 432 WP_216281604.1 protein YgfX Toxin
KNV89_RS13645 (KNV89_13645) 3060167..3060685 - 519 WP_216281605.1 flavodoxin FldB -
KNV89_RS13650 (KNV89_13650) 3060815..3062140 - 1326 WP_216281606.1 MFS transporter -
KNV89_RS13655 (KNV89_13655) 3062403..3063302 + 900 WP_216281608.1 site-specific tyrosine recombinase XerD -
KNV89_RS13660 (KNV89_13660) 3063392..3064108 + 717 WP_216281610.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 16794.50 Da        Isoelectric Point: 10.2155

>T205602 WP_216281604.1 NZ_CP076386:3059639-3060070 [Dickeya dadantii]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWPDGYAPLWLGLVTLVVFGFVCSQRIIKTRQGEISLHGENQLHWQQR
DWQIVRRPWLMRNGVLLSLRAVDGKGHQRLWLASDSMGNEEWRLLRQLLQQHSLQGTESSHHH

Download         Length: 432 bp

>T205602 NZ_CP101769:c2391-2125 [Klebsiella pneumoniae]
TTGGTCTGGACGATTAACTATTCCGATCGGGCGCTCAAATCGTTACGCAAGATGGACAAACAGAACGCACGACGGATTGT
GGATTTTATGAGTTTACGCATTGCAGTTGCTGCCGATCCTCGCCAGTCAGGGAAGCCGCTCAAAGGTGAGCTGGGCGAGT
TCTGGCGCTATCGGGTGGGAGATTATCGCGTTCTGTGTGAGATCCGAGATGACGAGCTTGTTATCCTTGCCGCCACGATT
GGACATCGCCGCGAAGTTTACGACTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10476.98 Da        Isoelectric Point: 5.5981

>AT205602 WP_013316361.1 NZ_CP076386:3059392-3059658 [Dickeya dadantii]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQQFIRLLQCDDPDLFNWLMNHGEPVDPALKRMVSLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT205602 NZ_CP101769:c2599-2375 [Klebsiella pneumoniae]
ATGCTTGCTATCCGGTTATCTGATGAGATTGAGTCCCGTCTGGACTCGCTGGCGAAGCAAACCGGCAGAACAAAGACGTT
TTATGCGCGGGAAGCAATACTGGCGCATCTGGAAGACCTGGAGGATTATTATCTTTCAGCAGAAACTGCTGCACGCGTTC
GCCGTGGTGATGAAGCAGTGCATTCGTCTGAAGACGTGAGGAAGTCACTTGGTCTGGACGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References