Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2125873..2126144 Replicon chromosome
Accession NZ_CP076274
Organism Escherichia coli strain P393-F10

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2125911..2126014 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2125873..2126144 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A7A10_RS10570 2123030..2124469 + 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
A7A10_RS10575 2124587..2124823 + 237 WP_001295499.1 YebV family protein -
A7A10_RS10580 2124928..2125119 + 192 WP_001296140.1 YebW family protein -
A7A10_RS10585 2125120..2125776 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2125873..2126144 + 272 - - Antitoxin
- 2125911..2126014 - 104 - - Toxin
A7A10_RS10590 2126172..2126513 - 342 WP_000976472.1 YebY family protein -
A7A10_RS10595 2126526..2127398 - 873 WP_257185900.1 copper homeostasis membrane protein CopD -
A7A10_RS10600 2127402..2127776 - 375 WP_000204699.1 CopC domain-containing protein YobA -
A7A10_RS10605 2127915..2128145 + 231 WP_000916763.1 DNA polymerase III subunit theta -
A7A10_RS10610 2128247..2128903 + 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
A7A10_RS10615 2128927..2129589 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T205228 NZ_CP076274:c2126014-2125911 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT205228 NZ_CP076274:2125873-2126144 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References