205012

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 287180..287565 Replicon chromosome
Accession NZ_CP076257
Organism Xanthomonas translucens pv. graminis strain ART-Xtg29

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KM433_RS01285 Protein ID WP_003469322.1
Coordinates 287431..287565 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0K2ZNU2
Locus tag KM433_RS01280 Protein ID WP_009574163.1
Coordinates 287180..287332 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KM433_RS01250 (KM433_01240) 282688..282960 - 273 WP_170867545.1 hypothetical protein -
KM433_RS01255 (KM433_01245) 283098..284093 + 996 WP_235444078.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KM433_RS01260 (KM433_01250) 284090..284830 + 741 WP_053114199.1 type III pantothenate kinase -
KM433_RS01265 (KM433_01255) 284840..285691 + 852 WP_053114197.1 SPOR domain-containing protein -
KM433_RS01275 (KM433_01265) 286112..287035 + 924 WP_009574164.1 arginase -
KM433_RS01280 (KM433_01270) 287180..287332 + 153 WP_009574163.1 entericidin A/B family lipoprotein Antitoxin
KM433_RS01285 (KM433_01275) 287431..287565 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KM433_RS01290 (KM433_01280) 287766..287981 + 216 WP_009574162.1 CsbD family protein -
KM433_RS01295 (KM433_01285) 288052..288894 - 843 WP_009574161.1 hypothetical protein -
KM433_RS01300 (KM433_01290) 289005..290315 + 1311 WP_009574157.1 tryptophan--tRNA ligase -
KM433_RS01305 (KM433_01295) 290594..291517 + 924 WP_009574155.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T205012 WP_003469322.1 NZ_CP076257:287431-287565 [Xanthomonas translucens pv. graminis]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T205012 NZ_CP101365:4694003-4694314 [Salmonella enterica]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTAGATAATTTTAAGCACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATATGATCGGGGTAATAAAGAATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5393.44 Da        Isoelectric Point: 8.1210

>AT205012 WP_009574163.1 NZ_CP076257:287180-287332 [Xanthomonas translucens pv. graminis]
MKRLFTLMMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVENKADDCKDGKC

Download         Length: 153 bp

>AT205012 NZ_CP101365:4694311-4694757 [Salmonella enterica]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAAGCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAAGCACTCAAC
CAACACCTGGAGAAAACGCCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTCAAACTACCAGCAGATGCCTTCATCGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K2ZNU2

References