Detailed information of TA system TA205011

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 1149317..1149822
• Replicon: chromosome
• Accession: NZ_CP076255
• Organism: Xanthomonas translucens pv. graminis strain NCPPB 3711

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KHF85_RS05080
• Protein ID: WP_284568739.1
• Coordinates: 1149317..1149574 (-)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1C3TRJ9
• Locus tag: KHF85_RS05085
• Protein ID: WP_003468816.1
• Coordinates: 1149571..1149822 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KHF85_RS05050 (KHF85_05030)	1144568..1145917	+	1350	WP_284568735.1	aminodeoxychorismate synthase component I	-
KHF85_RS05055 (KHF85_05035)	1145987..1147054	+	1068	WP_284568736.1	endolytic transglycosylase MltG	-
KHF85_RS05060 (KHF85_05040)	1147051..1147719	+	669	WP_284568737.1	dTMP kinase	-
KHF85_RS05065 (KHF85_05045)	1147716..1148678	+	963	WP_284568738.1	DNA polymerase III subunit delta'	-
KHF85_RS05070 (KHF85_05050)	1148675..1149028	+	354	WP_003479797.1	PilZ domain-containing protein	-
KHF85_RS05080 (KHF85_05060)	1149317..1149574	-	258	WP_284568739.1	Txe/YoeB family addiction module toxin	Toxin
KHF85_RS05085 (KHF85_05065)	1149571..1149822	-	252	WP_003468816.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
KHF85_RS05090 (KHF85_05070)	1149977..1150741	+	765	WP_284568740.1	endonuclease	-
KHF85_RS05095 (KHF85_05075)	1150738..1151460	-	723	WP_284568741.1	helix-turn-helix transcriptional regulator	-
KHF85_RS05100 (KHF85_05080)	1151582..1152031	+	450	WP_284568742.1	nuclear transport factor 2 family protein	-
KHF85_RS05105 (KHF85_05085)	1152774..1152983	+	210	WP_284568743.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10187.71 Da
• Isoelectric Point: 9.6587

>T205011 WP_284568739.1 NZ_CP076255:c1149574-1149317 [Xanthomonas translucens pv. graminis]
VTLQFSDNAWEDYLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPEPLRHALAGYWSRRINDEHRIVYKVEAGILLIAQV
RYHYV

Nucleotide

• Length: 258 bp

>T205011 NZ_CP101365:c4692770-4692459 [Salmonella enterica]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGAGGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9281.56 Da
• Isoelectric Point: 5.1186

>AT205011 WP_003468816.1 NZ_CP076255:c1149822-1149571 [Xanthomonas translucens pv. graminis]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Nucleotide

• Length: 252 bp

>AT205011 NZ_CP101365:c4692458-4692168 [Salmonella enterica]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAGCCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAGC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA

Structures

Antitoxin

• AlphaFold DB: A0A1C3TRJ9