205010

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 256660..257046 Replicon chromosome
Accession NZ_CP076255
Organism Xanthomonas translucens pv. graminis strain NCPPB 3711

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KHF85_RS01060 Protein ID WP_003469322.1
Coordinates 256912..257046 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag KHF85_RS01055 Protein ID WP_003469323.1
Coordinates 256660..256812 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KHF85_RS01025 (KHF85_01025) 252180..252452 - 273 WP_284568180.1 hypothetical protein -
KHF85_RS01030 (KHF85_01030) 252614..253585 + 972 WP_284568181.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KHF85_RS01035 (KHF85_01035) 253582..254322 + 741 WP_284568182.1 type III pantothenate kinase -
KHF85_RS01040 (KHF85_01040) 254332..255192 + 861 WP_284568183.1 SPOR domain-containing protein -
KHF85_RS01050 (KHF85_01050) 255592..256515 + 924 WP_064540906.1 arginase -
KHF85_RS01055 (KHF85_01055) 256660..256812 + 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
KHF85_RS01060 (KHF85_01060) 256912..257046 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KHF85_RS01065 (KHF85_01065) 257248..257480 + 233 Protein_205 CsbD family protein -
KHF85_RS01070 (KHF85_01070) 257533..258375 - 843 WP_284568184.1 hypothetical protein -
KHF85_RS01075 (KHF85_01075) 258486..259796 + 1311 WP_284568185.1 tryptophan--tRNA ligase -
KHF85_RS01080 (KHF85_01080) 260016..260939 + 924 Protein_208 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T205010 WP_003469322.1 NZ_CP076255:256912-257046 [Xanthomonas translucens pv. graminis]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T205010 NZ_CP101365:c4346146-4345655 [Salmonella enterica]
ATGATCTCCACCCCTGAGCCGCTTCATGCCGGACATATTCTTACTCCGTTTTGCTGCGGTGTGGATTCTATAGATAACTG
GCTGAAACAGCGGGCGATGAAAAATCAGACCACTGGCGCGTCCCGTACCTTTGTGTGTTGTGGCAGCGATTCGAACGTAC
TGGCCTATTACTCGCTGGCGTCCAGCGCGGTCACGACGAATACCTCCCCCGGTCGCTTTCGTCGCAATATGCCTGACCCG
ATTCCGGTTGTGGTATTGGGGCGTCTGGCGGTGGATAAATCGCTTCATGGGCAGGGCGTCGCTCGGGCGCTGGTACGCGA
CGCAGGGCTGCGGGTTATTCAGGTGGCGGAGACTATCGGCATTCGTGGGATGCTGGTTCACGCCCTGTCGGATGAAGCGC
GGGAATTTTATCAGCGGGTGGGGTTTGTACCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTG
GAGAGTGTTTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT205010 WP_003469323.1 NZ_CP076255:256660-256812 [Xanthomonas translucens pv. graminis]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT205010 NZ_CP101365:c4346436-4346143 [Salmonella enterica]
ATGCCAGCCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGTATCAAACCCGCCGAGCGCGATCTTATCGA
TCGAGCGGCGAAAGCCAGAGGGAAAAACCGCACAGACTTTGTGCTGGAAGCTGCCCGCGCTGCCGCAGAGGAAGCGCTTA
TCGAACAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGAGTTTCTCGTTCGTTTGGATCAAACACCTTCACCTAAT
GCCGCACTGCGTAAAACCATGCAGACCCCTGCGCCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References