205008

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 221013..221398 Replicon chromosome
Accession NZ_CP076254
Organism Xanthomonas translucens pv. graminis strain LMG 726

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KFS84_RS01015 Protein ID WP_003469322.1
Coordinates 221013..221147 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0K2ZNU2
Locus tag KFS84_RS01020 Protein ID WP_009574163.1
Coordinates 221246..221398 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFS84_RS00995 (KFS84_00985) 217061..217984 - 924 WP_009574155.1 MBL fold metallo-hydrolase -
KFS84_RS01000 (KFS84_00990) 218263..219573 - 1311 WP_009574157.1 tryptophan--tRNA ligase -
KFS84_RS01005 (KFS84_00995) 219684..220526 + 843 WP_009574161.1 hypothetical protein -
KFS84_RS01010 (KFS84_01000) 220597..220812 - 216 WP_009574162.1 CsbD family protein -
KFS84_RS01015 (KFS84_01005) 221013..221147 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KFS84_RS01020 (KFS84_01010) 221246..221398 - 153 WP_009574163.1 entericidin A/B family lipoprotein Antitoxin
KFS84_RS01025 (KFS84_01015) 221543..222466 - 924 WP_009574164.1 arginase -
KFS84_RS01035 (KFS84_01025) 222887..223738 - 852 WP_053114197.1 SPOR domain-containing protein -
KFS84_RS01040 (KFS84_01030) 223748..224488 - 741 WP_053114199.1 type III pantothenate kinase -
KFS84_RS01045 (KFS84_01035) 224485..225480 - 996 WP_235444078.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KFS84_RS01050 (KFS84_01040) 225618..225890 + 273 WP_170867545.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T205008 WP_003469322.1 NZ_CP076254:c221147-221013 [Xanthomonas translucens pv. graminis]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T205008 NZ_CP101365:3692971-3693228 [Salmonella enterica]
ATGAATGCCTCCGGCGTCAGCGTCCGCCACATCAACAGCAAAACCCACATGACCACCTATTACTCACAAATCCCCAGCCT
GCACCTTAAGGGTGACTGGCTGGAAGAAGCGGGATTTGAGACCGGGCGCGGCGTGACCGTGAAGATTTCACAGGGGTGTA
TTGTGCTGATGGCGGACAGTAACGAGGAGCAGAAGCTGCGCGAACAGCTTTACAAGGCTGAACAGGTGGTTAAGGGGATG
CGGGACGTGATTGTTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5393.44 Da        Isoelectric Point: 8.1210

>AT205008 WP_009574163.1 NZ_CP076254:c221398-221246 [Xanthomonas translucens pv. graminis]
MKRLFTLMMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVENKADDCKDGKC

Download         Length: 153 bp

>AT205008 NZ_CP101365:c3693146-3692878 [Salmonella enterica]
TCCGCCATCAGCACAATACACCCCTGTGAAATCTTCACGGTCACGCCGCGCCCGGTCTCAAATCCCGCTTCTTCCAGCCA
GTCACCCTTAAGGTGCAGGCTGGGGATTTGTGAGTAATAGGTGGTCATGTGGGTTTTGCTGTTGATGTGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTAATTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGCGAGTATGAGCGCGACAGCCTGCACCG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K2ZNU2

References