205007

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4088111..4088496 Replicon chromosome
Accession NZ_CP076253
Organism Xanthomonas translucens pv. graminis strain ART-Xtg2

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KM563_RS18170 Protein ID WP_003469322.1
Coordinates 4088111..4088245 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0K2ZNU2
Locus tag KM563_RS18175 Protein ID WP_009574163.1
Coordinates 4088344..4088496 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KM563_RS18150 (KM563_18045) 4084159..4085082 - 924 WP_009574155.1 MBL fold metallo-hydrolase -
KM563_RS18155 (KM563_18050) 4085361..4086671 - 1311 WP_009574157.1 tryptophan--tRNA ligase -
KM563_RS18160 (KM563_18055) 4086782..4087624 + 843 WP_009574161.1 hypothetical protein -
KM563_RS18165 (KM563_18060) 4087695..4087910 - 216 WP_009574162.1 CsbD family protein -
KM563_RS18170 (KM563_18065) 4088111..4088245 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KM563_RS18175 (KM563_18070) 4088344..4088496 - 153 WP_009574163.1 entericidin A/B family lipoprotein Antitoxin
KM563_RS18180 (KM563_18075) 4088641..4089564 - 924 WP_009574164.1 arginase -
KM563_RS18190 (KM563_18085) 4089985..4090836 - 852 WP_053114197.1 SPOR domain-containing protein -
KM563_RS18195 (KM563_18090) 4090846..4091586 - 741 WP_053114199.1 type III pantothenate kinase -
KM563_RS18200 (KM563_18095) 4091583..4092578 - 996 WP_235444078.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KM563_RS18205 (KM563_18100) 4092716..4092988 + 273 WP_170867545.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T205007 WP_003469322.1 NZ_CP076253:c4088245-4088111 [Xanthomonas translucens pv. graminis]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T205007 NZ_CP101365:3689774-3690031 [Salmonella enterica]
ATGAATGCCTCCGGCGTCAGCGTCCGCCATATCAACAGCGAAACCTGCATGTCCGCCTGTTACTCACAAATCCCCAGCCA
GCACCTTAAGGGTGACTGGCAGGAAGAAGCGGGATTTGAGACCGGGCGCAGCATCACCGTGAAGATTTCACAGGAGTGTA
TTGTGCTGATGGCGGACAGTAACGAGGAACAGAAGCTGCGCGAACAGCTTTACAAGGCTGAACAGGTGGTTAAGGGGATG
CGGGACGTGATTGTTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5393.44 Da        Isoelectric Point: 8.1210

>AT205007 WP_009574163.1 NZ_CP076253:c4088496-4088344 [Xanthomonas translucens pv. graminis]
MKRLFTLMMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVENKADDCKDGKC

Download         Length: 153 bp

>AT205007 NZ_CP101365:c3689949-3689617 [Salmonella enterica]
TCCGCCATCAGCACAATACACTCCTGTGAAATCTTCACGGTGATGCTGCGCCCGGTCTCAAATCCCGCTTCTTCCTGCCA
GTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGACATGCAGGTTTCGCTGTTGATATGGCGGACGCTGA
CGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGAGCTCAGGGTG
AGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCAGCCGGCTGCC
GGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K2ZNU2

References