205005

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4659213..4659598 Replicon chromosome
Accession NZ_CP076252
Organism Xanthomonas translucens pv. graminis strain ART-Xtg9

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KM579_RS20665 Protein ID WP_003469322.1
Coordinates 4659464..4659598 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0K2ZNU2
Locus tag KM579_RS20660 Protein ID WP_009574163.1
Coordinates 4659213..4659365 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KM579_RS20630 (KM579_20495) 4654721..4654993 - 273 WP_170867545.1 hypothetical protein -
KM579_RS20635 (KM579_20500) 4655131..4656126 + 996 WP_235444078.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KM579_RS20640 (KM579_20505) 4656123..4656863 + 741 WP_053114199.1 type III pantothenate kinase -
KM579_RS20645 (KM579_20510) 4656873..4657724 + 852 WP_053114197.1 SPOR domain-containing protein -
KM579_RS20655 (KM579_20520) 4658145..4659068 + 924 WP_009574164.1 arginase -
KM579_RS20660 (KM579_20525) 4659213..4659365 + 153 WP_009574163.1 entericidin A/B family lipoprotein Antitoxin
KM579_RS20665 (KM579_20530) 4659464..4659598 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KM579_RS20670 (KM579_20535) 4659799..4660014 + 216 WP_009574162.1 CsbD family protein -
KM579_RS20675 (KM579_20540) 4660085..4660927 - 843 WP_009574161.1 hypothetical protein -
KM579_RS20680 (KM579_20545) 4661038..4662348 + 1311 WP_074379035.1 tryptophan--tRNA ligase -
KM579_RS20685 (KM579_20550) 4662627..4663550 + 924 WP_009574155.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T205005 WP_003469322.1 NZ_CP076252:4659464-4659598 [Xanthomonas translucens pv. graminis]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T205005 NZ_CP101365:2415223-2415507 [Salmonella enterica]
ATGACTTATAAGCTGGCATTTAACGAATCTGCACTAAAAGAGTGGAAAAAGCTGGGACATACTATACAGGAACAGTTTAA
AAAAAAGTTACGGGAACGGCTTGAAAACCCTCGGGTTCCGGCTTCTCAATTACATGGAAGAAAGGATCAGTACAAAATTA
AGCTGCGTGGTGCAGGATACAGACTGGTGTACAGCGTCGAAGATGAAATTATCACGGTAACTGTCATTGGCGTTGGAAAG
CGTGAAAATGATGCCGTCTACAAAGTGACACGACACAGAAGCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5393.44 Da        Isoelectric Point: 8.1210

>AT205005 WP_009574163.1 NZ_CP076252:4659213-4659365 [Xanthomonas translucens pv. graminis]
MKRLFTLMMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVENKADDCKDGKC

Download         Length: 153 bp

>AT205005 NZ_CP101365:2414985-2415233 [Salmonella enterica]
ATGGCATTTCAAATTTTAACGACTACTGCAGCAAGCATTACTGAACTGAAACGTGACCCAATGGGAACTTTCAATGCCGG
AGATGGCGCTCCAGTTGCCATTCTTAACCGTAATGAACCGGCTTTCTACTGTGTGCCTCCGGCACTTTATGCTCATCTTA
TGGATATTCTTGAGGATGAAGAACTCGGTCGTATTATCGATGAGCGTGCGAATGAACGCGTCATTGAGGTCAACATTGAT
GACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K2ZNU2

References