Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 377911..378296 Replicon chromosome
Accession NZ_CP076250
Organism Xanthomonas translucens pv. poae strain LMG 728

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KM539_RS01710 Protein ID WP_003469322.1
Coordinates 378162..378296 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0K2ZNU2
Locus tag KM539_RS01705 Protein ID WP_009574163.1
Coordinates 377911..378063 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KM539_RS01670 (KM539_01665) 373139..373417 + 279 WP_053841296.1 hypothetical protein -
KM539_RS01675 (KM539_01670) 373525..373887 - 363 WP_053841295.1 hypothetical protein -
KM539_RS01680 (KM539_01675) 373957..374472 + 516 WP_053841294.1 hypothetical protein -
KM539_RS01685 (KM539_01680) 374564..375076 - 513 WP_053841293.1 hypothetical protein -
KM539_RS01690 (KM539_01685) 375189..376418 - 1230 WP_053841292.1 integrase arm-type DNA-binding domain-containing protein -
KM539_RS01700 (KM539_01695) 376843..377766 + 924 WP_053841291.1 arginase -
KM539_RS01705 (KM539_01700) 377911..378063 + 153 WP_009574163.1 entericidin A/B family lipoprotein Antitoxin
KM539_RS01710 (KM539_01705) 378162..378296 + 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KM539_RS01715 (KM539_01710) 378497..378712 + 216 WP_053841290.1 CsbD family protein -
KM539_RS01720 (KM539_01715) 378783..379625 - 843 WP_053841289.1 hypothetical protein -
KM539_RS01725 (KM539_01720) 379736..381136 + 1401 WP_053841288.1 tryptophan--tRNA ligase -
KM539_RS01730 (KM539_01725) 381192..382115 + 924 WP_053841287.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T204996 WP_003469322.1 NZ_CP076250:378162-378296 [Xanthomonas translucens pv. poae]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T204996 NZ_CP101310:c4788824-4788474 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTT
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5393.44 Da        Isoelectric Point: 8.1210

>AT204996 WP_009574163.1 NZ_CP076250:377911-378063 [Xanthomonas translucens pv. poae]
MKRLFTLMMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVENKADDCKDGKC

Download         Length: 153 bp

>AT204996 NZ_CP101310:c4789069-4788818 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCGTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGCGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K2ZNU2

References