204995

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4418965..4419350 Replicon chromosome
Accession NZ_CP076249
Organism Xanthomonas translucens pv. hordei strain UPB458

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KFS86_RS19200 Protein ID WP_003469322.1
Coordinates 4418965..4419099 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag KFS86_RS19205 Protein ID WP_003469323.1
Coordinates 4419198..4419350 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFS86_RS19185 (KFS86_19145) 4415415..4416338 - 924 WP_064521685.1 MBL fold metallo-hydrolase -
KFS86_RS19190 (KFS86_19150) 4416394..4417794 - 1401 WP_060744654.1 tryptophan--tRNA ligase -
KFS86_RS19195 (KFS86_19155) 4417905..4418756 + 852 WP_060744655.1 hypothetical protein -
KFS86_RS19200 (KFS86_19160) 4418965..4419099 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KFS86_RS19205 (KFS86_19165) 4419198..4419350 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
KFS86_RS19210 (KFS86_19170) 4419494..4420417 - 924 WP_058360588.1 arginase -
KFS86_RS19220 (KFS86_19180) 4420805..4421641 - 837 WP_161993387.1 SPOR domain-containing protein -
KFS86_RS19225 (KFS86_19185) 4421651..4422391 - 741 WP_004427869.1 type III pantothenate kinase -
KFS86_RS19230 (KFS86_19190) 4422388..4423383 - 996 WP_153476936.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KFS86_RS19235 (KFS86_19195) 4423521..4423793 + 273 WP_003476582.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-39)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T204995 WP_003469322.1 NZ_CP076249:c4419099-4418965 [Xanthomonas translucens pv. hordei]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T204995 NZ_CP101310:c4505244-4504930 [Escherichia coli]
ATGCAATTTACGGTATACCGCAGTCGCAGCAGGAACGCCGCGTTTCCCTTTGTTATCGATGTTACCAGCGACATTATTGG
TGTGATTAATCGCCGTATTGTTATTCCATTAACACCTATTGAACGATTTATCCGTATTCGCCCACCAGAACGGCTTAACC
CAATCCTTTTACTGGTAGACGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCGCACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT204995 WP_003469323.1 NZ_CP076249:c4419350-4419198 [Xanthomonas translucens pv. hordei]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT204995 NZ_CP101310:c4505480-4505247 [Escherichia coli]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACG
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References