Detailed information of TA system TA204994

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 4126784..4128350
• Replicon: chromosome
• Accession: NZ_CP076249
• Organism: Xanthomonas translucens pv. hordei strain UPB458

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: KFS86_RS17950
• Protein ID: WP_003480647.1
• Coordinates: 4126784..4128040 (+)
• Length: 419 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: -
• Locus tag: KFS86_RS17955
• Protein ID: WP_003480646.1
• Coordinates: 4128054..4128350 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KFS86_RS17940 (KFS86_17900)	4124095..4125036	-	942	WP_003465367.1	alpha-E domain-containing protein	-
KFS86_RS17945 (KFS86_17905)	4125036..4126484	-	1449	WP_003480648.1	circularly permuted type 2 ATP-grasp protein	-
KFS86_RS17950 (KFS86_17910)	4126784..4128040	+	1257	WP_003480647.1	XopAJ/AvrRxo1 family type III secretion system effector zeta toxin	Toxin
KFS86_RS17955 (KFS86_17915)	4128054..4128350	+	297	WP_003480646.1	hypothetical protein	Antitoxin
KFS86_RS17960 (KFS86_17920)	4128523..4128798	-	276	WP_128809232.1	hypothetical protein	-
KFS86_RS17965 (KFS86_17925)	4128879..4129232	-	354	WP_003480645.1	dihydroneopterin aldolase	-
KFS86_RS17970 (KFS86_17930)	4129205..4130380	-	1176	WP_237656306.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	-
KFS86_RS17975 (KFS86_17935)	4130502..4130717	+	216	WP_003465342.1	30S ribosomal protein S21	-
KFS86_RS17980 (KFS86_17940)	4130997..4131446	+	450	WP_003480639.1	GatB/YqeY domain-containing protein	-
KFS86_RS17985 (KFS86_17945)	4131581..4132495	+	915	WP_003465336.1	YihY/virulence factor BrkB family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (148-285)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 419 a.a.
• Molecular weight: 45042.67 Da
• Isoelectric Point: 6.6145

>T204994 WP_003480647.1 NZ_CP076249:4126784-4128040 [Xanthomonas translucens pv. hordei]
MKGKISNACKPDITPILVDGLASTATQGAADDSASRLPQQALLDGLQERPQALKKSNSADWSARTLPQWAPGPGTSSKAL
LIQSPPHPTSSDEMFGLGELPAPGKARWEYLTKTENWHPERQELHSRLLSQARTASLRLAESIESDGYPPTLFALRGNTA
TGKTRIATKTIPVLANALKKSSGGGCINPDIFKRSLAESQGEAMKLSSAQVHAESCVLADRLENELRSQRTTSGAMASIL
VDKRLANTHEVDSYVSLAKETGRKVELCDIDAPLERSLMGVLQRSPGGDDPRPPYVAVANGFSTVRSNRLDVIDRFLSNP
TLGSYRLFGTNEKGEKVMVASVADGELSIHDPQLYESITAPEDFNSGDKGEQVIDTALIDRLSNSIDDPKRATDARAALE
KYKGMTWSNALAAHSSLI

Nucleotide

• Length: 1257 bp

>T204994 NZ_CP101310:4076516-4076734 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11088.54 Da
• Isoelectric Point: 7.3576

>AT204994 WP_003480646.1 NZ_CP076249:4128054-4128350 [Xanthomonas translucens pv. hordei]
MTHLKGADALALHKKLKERNASLRSAELDSAKALAHESGKERFNLEKLESICDTTQAGRITDPNDRQAIYEQMYYVEHPK
VSTLQEFARIVVTISSWS

Nucleotide

• Length: 297 bp

>AT204994 NZ_CP101310:4076116-4076490 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACTCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG