Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-StbC |
| Location | 2268281..2268951 | Replicon | chromosome |
| Accession | NZ_CP076249 | ||
| Organism | Xanthomonas translucens pv. hordei strain UPB458 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | KFS86_RS09820 | Protein ID | WP_058361064.1 |
| Coordinates | 2268532..2268951 (+) | Length | 140 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | A0A2S7EM03 |
| Locus tag | KFS86_RS09815 | Protein ID | WP_003473422.1 |
| Coordinates | 2268281..2268535 (+) | Length | 85 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFS86_RS09795 (KFS86_09770) | 2263818..2264783 | - | 966 | WP_065898826.1 | IS1595 family transposase | - |
| KFS86_RS09800 (KFS86_09775) | 2265300..2266435 | + | 1136 | WP_153476785.1 | IS3 family transposase | - |
| KFS86_RS09805 (KFS86_09780) | 2266471..2266971 | + | 501 | Protein_1922 | replication protein C, IncQ-type | - |
| KFS86_RS09810 (KFS86_09785) | 2267588..2267869 | + | 282 | WP_058361065.1 | TraK family protein | - |
| KFS86_RS09815 (KFS86_09790) | 2268281..2268535 | + | 255 | WP_003473422.1 | hypothetical protein | Antitoxin |
| KFS86_RS09820 (KFS86_09795) | 2268532..2268951 | + | 420 | WP_058361064.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| KFS86_RS09825 (KFS86_09800) | 2269108..2269878 | + | 771 | WP_058361066.1 | P-type conjugative transfer protein TrbJ | - |
| KFS86_RS09830 (KFS86_09805) | 2269889..2270047 | + | 159 | WP_153476784.1 | hypothetical protein | - |
| KFS86_RS09835 (KFS86_09810) | 2270049..2271449 | + | 1401 | WP_058361063.1 | P-type conjugative transfer protein TrbL | - |
| KFS86_RS09840 (KFS86_09815) | 2271563..2271805 | + | 243 | WP_033981742.1 | type I toxin-antitoxin system ptaRNA1 family toxin | - |
| KFS86_RS09845 (KFS86_09820) | 2271817..2272101 | + | 285 | WP_058361062.1 | hypothetical protein | - |
| KFS86_RS09850 (KFS86_09825) | 2272104..2272472 | + | 369 | WP_058361061.1 | conjugal transfer transcriptional regulator TraJ | - |
| KFS86_RS09855 (KFS86_09830) | 2272440..2272829 | - | 390 | Protein_1932 | replication protein C, IncQ-type | - |
| KFS86_RS09860 (KFS86_09835) | 2272801..2273679 | - | 879 | WP_058361060.1 | helicase RepA family protein | - |
| KFS86_RS09865 (KFS86_09840) | 2273683..2273916 | - | 234 | WP_003472509.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 2263362..2283084 | 19722 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 14945.19 Da Isoelectric Point: 4.9167
>T204993 WP_058361064.1 NZ_CP076249:2268532-2268951 [Xanthomonas translucens pv. hordei]
MIVLDTNVVSEAMKPEPDPAVRAWLNEQVAETLYLSSVTLAELLFGIGALPNGKRKKGLGEALDGLLELFSERVLMFDTE
AARNYAELAVKARIAGKGFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHR
MIVLDTNVVSEAMKPEPDPAVRAWLNEQVAETLYLSSVTLAELLFGIGALPNGKRKKGLGEALDGLLELFSERVLMFDTE
AARNYAELAVKARIAGKGFPTPDGYIGAIAASKGFIVATRDTSPFEAAGLTVINPWNHR
Download Length: 420 bp
>T204993 NZ_CP101310:c3147068-3146694 [Escherichia coli]
ATGAAAACATTATCCGACACACATGTACGGGAGGTATCTCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAT
CCGACTGCTGGACCAGCATTATGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTTAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACCTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCTTGGGTAAGTATCCGGAGGCGAAATGA
ATGAAAACATTATCCGACACACATGTACGGGAGGTATCTCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAT
CCGACTGCTGGACCAGCATTATGGCCTCACACTGAATGACACACCGTTTGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTTAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACCTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCTTGGGTAAGTATCCGGAGGCGAAATGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9507.88 Da Isoelectric Point: 7.2071
>AT204993 WP_003473422.1 NZ_CP076249:2268281-2268535 [Xanthomonas translucens pv. hordei]
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSQKRIRMGDALAELGRRVGLTNDDFAVLDQVRDKVPAEP
MRFE
MAILTVRNVPDEVHRALRLRAAEHGRSTEAEVREILESAVKSQKRIRMGDALAELGRRVGLTNDDFAVLDQVRDKVPAEP
MRFE
Download Length: 255 bp
>AT204993 NZ_CP101310:c3147489-3147115 [Escherichia coli]
GTGTCAGACAAACTCTCCGGGATAACTCATCCCGATGACAATCACGACCGCCCCTGGTGGGGGCTTCCCTGCACAGTGAG
GCCCTGTTTTGGCGCTCGTCTGGTGCAAGAGGGTAACCGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGCT
TCAGCGACGCAGATGCATACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGATATCAGCATACCGTCACGCTGAATGCAAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCAGCACTCGCAACCACCTCATAA
GTGTCAGACAAACTCTCCGGGATAACTCATCCCGATGACAATCACGACCGCCCCTGGTGGGGGCTTCCCTGCACAGTGAG
GCCCTGTTTTGGCGCTCGTCTGGTGCAAGAGGGTAACCGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGCT
TCAGCGACGCAGATGCATACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGATATCAGCATACCGTCACGCTGAATGCAAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCAGCACTCGCAACCACCTCATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|