Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1068731..1069236 Replicon chromosome
Accession NZ_CP076249
Organism Xanthomonas translucens pv. hordei strain UPB458

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KFS86_RS04890 Protein ID WP_058195736.1
Coordinates 1068731..1068988 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A1C3TRJ9
Locus tag KFS86_RS04895 Protein ID WP_003468816.1
Coordinates 1068985..1069236 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFS86_RS04860 (KFS86_04835) 1063965..1065314 + 1350 WP_058360629.1 aminodeoxychorismate synthase component I -
KFS86_RS04865 (KFS86_04840) 1065390..1066451 + 1062 WP_058360633.1 endolytic transglycosylase MltG -
KFS86_RS04870 (KFS86_04845) 1066448..1067116 + 669 WP_003479795.1 dTMP kinase -
KFS86_RS04875 (KFS86_04850) 1067113..1068090 + 978 WP_003479796.1 DNA polymerase III subunit delta' -
KFS86_RS04880 (KFS86_04855) 1068087..1068440 + 354 WP_003479797.1 PilZ domain-containing protein -
KFS86_RS04890 (KFS86_04865) 1068731..1068988 - 258 WP_058195736.1 Txe/YoeB family addiction module toxin Toxin
KFS86_RS04895 (KFS86_04870) 1068985..1069236 - 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KFS86_RS04900 (KFS86_04875) 1069345..1069878 + 534 Protein_953 endonuclease -
KFS86_RS04905 (KFS86_04880) 1069875..1070597 - 723 WP_058360631.1 helix-turn-helix transcriptional regulator -
KFS86_RS04910 (KFS86_04885) 1070721..1071164 + 444 WP_058360632.1 nuclear transport factor 2 family protein -
KFS86_RS04915 1071334..1071483 + 150 WP_230939940.1 type II toxin-antitoxin system RelE/ParE family toxin -
KFS86_RS04920 (KFS86_04895) 1071603..1071785 + 183 WP_196480047.1 hypothetical protein -
KFS86_RS20235 1072624..1072755 + 132 WP_269113130.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1071760..1072158 398


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10216.73 Da        Isoelectric Point: 9.7381

>T204991 WP_058195736.1 NZ_CP076249:c1068988-1068731 [Xanthomonas translucens pv. hordei]
VTLQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPERLRHALAGYWSRRINDEHRIVYKVEAGMLLIAQV
RYHYV

Download         Length: 258 bp

>T204991 NZ_CP101310:2921520-2921627 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9281.56 Da        Isoelectric Point: 5.1186

>AT204991 WP_003468816.1 NZ_CP076249:c1069236-1068985 [Xanthomonas translucens pv. hordei]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Download         Length: 252 bp

>AT204991 NZ_CP101310:c2921467-2921406 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TRJ9

References