204990

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4431545..4431930 Replicon chromosome
Accession NZ_CP076248
Organism Xanthomonas translucens pv. hordei strain UPB947

Toxin (Protein)


Gene name EcnB Uniprot ID A0A0K2ZHE5
Locus tag KFS83_RS19270 Protein ID WP_003469322.1
Coordinates 4431545..4431679 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1C3TTT1
Locus tag KFS83_RS19275 Protein ID WP_003469323.1
Coordinates 4431778..4431930 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFS83_RS19255 (KFS83_19140) 4427995..4428918 - 924 WP_064521685.1 MBL fold metallo-hydrolase -
KFS83_RS19260 (KFS83_19145) 4428974..4430374 - 1401 WP_060744654.1 tryptophan--tRNA ligase -
KFS83_RS19265 (KFS83_19150) 4430485..4431336 + 852 WP_060744655.1 hypothetical protein -
KFS83_RS19270 (KFS83_19155) 4431545..4431679 - 135 WP_003469322.1 entericidin A/B family lipoprotein Toxin
KFS83_RS19275 (KFS83_19160) 4431778..4431930 - 153 WP_003469323.1 entericidin A/B family lipoprotein Antitoxin
KFS83_RS19280 (KFS83_19165) 4432074..4432997 - 924 WP_058360588.1 arginase -
KFS83_RS19290 (KFS83_19175) 4433385..4434221 - 837 WP_161993387.1 SPOR domain-containing protein -
KFS83_RS19295 (KFS83_19180) 4434231..4434971 - 741 WP_004427869.1 type III pantothenate kinase -
KFS83_RS19300 (KFS83_19185) 4434968..4435963 - 996 WP_153476936.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
KFS83_RS19305 (KFS83_19190) 4436101..4436373 + 273 WP_003476582.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-39)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4604.40 Da        Isoelectric Point: 9.2977

>T204990 WP_003469322.1 NZ_CP076248:c4431679-4431545 [Xanthomonas translucens pv. hordei]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN

Download         Length: 135 bp

>T204990 NZ_CP101310:2920984-2921091 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTAGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGACTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5350.35 Da        Isoelectric Point: 8.1210

>AT204990 WP_003469323.1 NZ_CP076248:c4431930-4431778 [Xanthomonas translucens pv. hordei]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC

Download         Length: 153 bp

>AT204990 NZ_CP101310:c2920937-2920871 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0K2ZHE5


Antitoxin

Source ID Structure
AlphaFold DB A0A1C3TTT1

References