Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | EcnAB/- |
Location | 4431545..4431930 | Replicon | chromosome |
Accession | NZ_CP076248 | ||
Organism | Xanthomonas translucens pv. hordei strain UPB947 |
Toxin (Protein)
Gene name | EcnB | Uniprot ID | A0A0K2ZHE5 |
Locus tag | KFS83_RS19270 | Protein ID | WP_003469322.1 |
Coordinates | 4431545..4431679 (-) | Length | 45 a.a. |
Antitoxin (Protein)
Gene name | EcnA | Uniprot ID | A0A1C3TTT1 |
Locus tag | KFS83_RS19275 | Protein ID | WP_003469323.1 |
Coordinates | 4431778..4431930 (-) | Length | 51 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KFS83_RS19255 (KFS83_19140) | 4427995..4428918 | - | 924 | WP_064521685.1 | MBL fold metallo-hydrolase | - |
KFS83_RS19260 (KFS83_19145) | 4428974..4430374 | - | 1401 | WP_060744654.1 | tryptophan--tRNA ligase | - |
KFS83_RS19265 (KFS83_19150) | 4430485..4431336 | + | 852 | WP_060744655.1 | hypothetical protein | - |
KFS83_RS19270 (KFS83_19155) | 4431545..4431679 | - | 135 | WP_003469322.1 | entericidin A/B family lipoprotein | Toxin |
KFS83_RS19275 (KFS83_19160) | 4431778..4431930 | - | 153 | WP_003469323.1 | entericidin A/B family lipoprotein | Antitoxin |
KFS83_RS19280 (KFS83_19165) | 4432074..4432997 | - | 924 | WP_058360588.1 | arginase | - |
KFS83_RS19290 (KFS83_19175) | 4433385..4434221 | - | 837 | WP_161993387.1 | SPOR domain-containing protein | - |
KFS83_RS19295 (KFS83_19180) | 4434231..4434971 | - | 741 | WP_004427869.1 | type III pantothenate kinase | - |
KFS83_RS19300 (KFS83_19185) | 4434968..4435963 | - | 996 | WP_153476936.1 | bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA | - |
KFS83_RS19305 (KFS83_19190) | 4436101..4436373 | + | 273 | WP_003476582.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 45 a.a. Molecular weight: 4604.40 Da Isoelectric Point: 9.2977
>T204990 WP_003469322.1 NZ_CP076248:c4431679-4431545 [Xanthomonas translucens pv. hordei]
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN
MKRTFAWMLLAMFSVGLLSGCNTVAGAGKDVKSAGEKVEDAAKN
Download Length: 135 bp
>T204990 NZ_CP101310:2920984-2921091 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTAGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGACTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTAGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGACTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 51 a.a. Molecular weight: 5350.35 Da Isoelectric Point: 8.1210
>AT204990 WP_003469323.1 NZ_CP076248:c4431930-4431778 [Xanthomonas translucens pv. hordei]
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC
MKRLFTLTMLTLFCAGMLTGCNTMAGAGKDMQKAGDKVETKADDCKDGKC
Download Length: 153 bp
>AT204990 NZ_CP101310:c2920937-2920871 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K2ZHE5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1C3TTT1 |