Detailed information of TA system TA204989

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): omega-epsilon-zeta/-
• Location: 4139371..4140937
• Replicon: chromosome
• Accession: NZ_CP076248
• Organism: Xanthomonas translucens pv. hordei strain UPB947

Toxin (Protein)

• Gene name: avrRxo1
• Uniprot ID: -
• Locus tag: KFS83_RS18005
• Protein ID: WP_003480647.1
• Coordinates: 4139371..4140627 (+)
• Length: 419 a.a.

Antitoxin (Protein)

• Gene name: arc1
• Uniprot ID: -
• Locus tag: KFS83_RS18010
• Protein ID: WP_003480646.1
• Coordinates: 4140641..4140937 (+)
• Length: 99 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KFS83_RS17995 (KFS83_17895)	4136682..4137623	-	942	WP_003465367.1	alpha-E domain-containing protein	-
KFS83_RS18000 (KFS83_17900)	4137623..4139071	-	1449	WP_003480648.1	circularly permuted type 2 ATP-grasp protein	-
KFS83_RS18005 (KFS83_17905)	4139371..4140627	+	1257	WP_003480647.1	XopAJ/AvrRxo1 family type III secretion system effector zeta toxin	Toxin
KFS83_RS18010 (KFS83_17910)	4140641..4140937	+	297	WP_003480646.1	hypothetical protein	Antitoxin
KFS83_RS18015 (KFS83_17915)	4141110..4141385	-	276	WP_128809232.1	hypothetical protein	-
KFS83_RS18020 (KFS83_17920)	4141466..4141819	-	354	WP_003480645.1	dihydroneopterin aldolase	-
KFS83_RS18025 (KFS83_17925)	4141792..4142967	-	1176	WP_237656306.1	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	-
KFS83_RS18030 (KFS83_17930)	4143089..4143304	+	216	WP_003465342.1	30S ribosomal protein S21	-
KFS83_RS18035 (KFS83_17935)	4143584..4144033	+	450	WP_003480639.1	GatB/YqeY domain-containing protein	-
KFS83_RS18040 (KFS83_17940)	4144168..4145082	+	915	WP_003465336.1	YihY/virulence factor BrkB family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Zeta toxin domain (148-285)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 419 a.a.
• Molecular weight: 45042.67 Da
• Isoelectric Point: 6.6145

>T204989 WP_003480647.1 NZ_CP076248:4139371-4140627 [Xanthomonas translucens pv. hordei]
MKGKISNACKPDITPILVDGLASTATQGAADDSASRLPQQALLDGLQERPQALKKSNSADWSARTLPQWAPGPGTSSKAL
LIQSPPHPTSSDEMFGLGELPAPGKARWEYLTKTENWHPERQELHSRLLSQARTASLRLAESIESDGYPPTLFALRGNTA
TGKTRIATKTIPVLANALKKSSGGGCINPDIFKRSLAESQGEAMKLSSAQVHAESCVLADRLENELRSQRTTSGAMASIL
VDKRLANTHEVDSYVSLAKETGRKVELCDIDAPLERSLMGVLQRSPGGDDPRPPYVAVANGFSTVRSNRLDVIDRFLSNP
TLGSYRLFGTNEKGEKVMVASVADGELSIHDPQLYESITAPEDFNSGDKGEQVIDTALIDRLSNSIDDPKRATDARAALE
KYKGMTWSNALAAHSSLI

Nucleotide

• Length: 1257 bp

>T204989 NZ_CP101310:c2621697-2621521 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin

Protein

• Length: 99 a.a.
• Molecular weight: 11088.54 Da
• Isoelectric Point: 7.3576

>AT204989 WP_003480646.1 NZ_CP076248:4140641-4140937 [Xanthomonas translucens pv. hordei]
MTHLKGADALALHKKLKERNASLRSAELDSAKALAHESGKERFNLEKLESICDTTQAGRITDPNDRQAIYEQMYYVEHPK
VSTLQEFARIVVTISSWS

Nucleotide

• Length: 297 bp

>AT204989 NZ_CP101310:c2621475-2621059 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
CCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCGTTACCTTCGCCATTAAATAGTCACGATCATTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAAAT
TACTCGCTTATTTAACTTGCACCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCTAAGGCGCTTGGCAAAGAGTTAT
CACTGGTGATGGTTTGA