Detailed information of TA system TA204986

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YoeB-YefM
• Location: 1068695..1069200
• Replicon: chromosome
• Accession: NZ_CP076248
• Organism: Xanthomonas translucens pv. hordei strain UPB947

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: KFS83_RS04890
• Protein ID: WP_058195736.1
• Coordinates: 1068695..1068952 (-)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: A0A1C3TRJ9
• Locus tag: KFS83_RS04895
• Protein ID: WP_003468816.1
• Coordinates: 1068949..1069200 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KFS83_RS04860 (KFS83_04835)	1063929..1065278	+	1350	WP_058360629.1	aminodeoxychorismate synthase component I	-
KFS83_RS04865 (KFS83_04840)	1065354..1066415	+	1062	WP_058360633.1	endolytic transglycosylase MltG	-
KFS83_RS04870 (KFS83_04845)	1066412..1067080	+	669	WP_003479795.1	dTMP kinase	-
KFS83_RS04875 (KFS83_04850)	1067077..1068054	+	978	WP_003479796.1	DNA polymerase III subunit delta'	-
KFS83_RS04880 (KFS83_04855)	1068051..1068404	+	354	WP_003479797.1	PilZ domain-containing protein	-
KFS83_RS04890 (KFS83_04865)	1068695..1068952	-	258	WP_058195736.1	Txe/YoeB family addiction module toxin	Toxin
KFS83_RS04895 (KFS83_04870)	1068949..1069200	-	252	WP_003468816.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
KFS83_RS04900 (KFS83_04875)	1069309..1069842	+	534	Protein_954	endonuclease	-
KFS83_RS04905 (KFS83_04880)	1069839..1070561	-	723	WP_058360631.1	helix-turn-helix transcriptional regulator	-
KFS83_RS04910 (KFS83_04885)	1070685..1071128	+	444	WP_058360632.1	nuclear transport factor 2 family protein	-
KFS83_RS04915	1071298..1071447	+	150	WP_230939940.1	type II toxin-antitoxin system RelE/ParE family toxin	-
KFS83_RS04920 (KFS83_04895)	1071567..1071749	+	183	WP_196480047.1	hypothetical protein	-
KFS83_RS04930	1072588..1072719	+	132	WP_269113130.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1071724..1072122	398

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10216.73 Da
• Isoelectric Point: 9.7381

>T204986 WP_058195736.1 NZ_CP076248:c1068952-1068695 [Xanthomonas translucens pv. hordei]
VTLQFSDNAWEDDLYWQQTDKKMLKRINDLIKAIQRDPFQGVGKPERLRHALAGYWSRRINDEHRIVYKVEAGMLLIAQV
RYHYV

Nucleotide

• Length: 258 bp

>T204986 NZ_CP101310:1866668-1866919 [Escherichia coli]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9281.56 Da
• Isoelectric Point: 5.1186

>AT204986 WP_003468816.1 NZ_CP076248:c1069200-1068949 [Xanthomonas translucens pv. hordei]
MDTITYSAARAALADTMERVVNNHEPVIITRSREQSVVMLSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKARD
LAE

Nucleotide

• Length: 252 bp

>AT204986 NZ_CP101310:1866916-1867170 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Structures

Antitoxin

• AlphaFold DB: A0A1C3TRJ9