Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2231419..2231690 Replicon chromosome
Accession NZ_CP076245
Organism Escherichia coli O157:H7 strain Balcarce_24.2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2231549..2231652 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2231419..2231690 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JKN64_RS11110 2227974..2228636 - 663 WP_000944243.1 exodeoxyribonuclease X -
JKN64_RS11115 2228660..2229316 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
JKN64_RS11120 2229418..2229648 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JKN64_RS11125 2229787..2230161 + 375 WP_000168751.1 CopC domain-containing protein YobA -
JKN64_RS11130 2230165..2231037 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
JKN64_RS11135 2231050..2231391 + 342 WP_000976483.1 YebY family protein -
- 2231419..2231690 - 272 - - Antitoxin
- 2231549..2231652 + 104 - - Toxin
JKN64_RS11140 2231787..2232443 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
JKN64_RS11145 2232444..2232635 - 192 WP_001296140.1 YebW family protein -
JKN64_RS11150 2232740..2232976 - 237 WP_001295499.1 YebV family protein -
JKN64_RS11155 2233094..2234533 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T204964 NZ_CP076245:2231549-2231652 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT204964 NZ_CP076245:c2231690-2231419 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References