Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2338763..2339034 Replicon chromosome
Accession NZ_CP076243
Organism Escherichia coli O157:H7 strain Balcarce_14.2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2338893..2338996 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2338763..2339034 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JKN69_RS11960 2335318..2335980 - 663 WP_000944244.1 exodeoxyribonuclease X -
JKN69_RS11965 2336004..2336660 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
JKN69_RS11970 2336762..2336992 - 231 WP_000916763.1 DNA polymerase III subunit theta -
JKN69_RS11975 2337131..2337505 + 375 WP_000168751.1 CopC domain-containing protein YobA -
JKN69_RS11980 2337509..2338381 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
JKN69_RS11985 2338394..2338735 + 342 WP_000976483.1 YebY family protein -
- 2338763..2339034 - 272 - - Antitoxin
- 2338893..2338996 + 104 - - Toxin
JKN69_RS11990 2339131..2339787 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
JKN69_RS11995 2339788..2339979 - 192 WP_001296140.1 YebW family protein -
JKN69_RS12000 2340084..2340320 - 237 WP_001295499.1 YebV family protein -
JKN69_RS12005 2340438..2341877 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T204936 NZ_CP076243:2338893-2338996 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT204936 NZ_CP076243:c2339034-2338763 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References